MRC Holland Introduces New digitalMLPA Panel for Expanded Carrier Screening of 26 Inherited Disorders
MRC Holland has launched the NXtec D038 Carrier Plus, a new digitalMLPA panel designed to enhance carrier status determination for 26 inherited disorders. This panel expands upon the existing D028 Carrier Panel 1, which offers focused coverage for key inherited disorders. The D038 Carrier Plus now includes a broader range of autosomal recessive and X-linked disorders, such as fragile X syndrome, Gaucher disease, Tay-Sachs disease, Bloom syndrome, galactosemia, phenylketonuria, and hemophilia A. The technology, digitalMLPA, combines the specificity of MLPA with the high-throughput capabilities of next-generation sequencing (NGS). This allows for the simultaneous detection of copy number variants and selected genetic variants, particularly in complex genomic regions that are often challenging to assess with standard sequencing methods. The company states that this new panel provides laboratories with the flexibility to choose between focused and expanded disease coverage, integrating seamlessly into existing...