Sharif and Trump are expected to discuss a wide-ranging agenda, including the devastating floods in Pakistan and the fallout of Israel's attack on Qatar, reports said.
The meeting comes at a time when the US has shown interest in forging closer trade ties with Pakistan.
Islamabad has made concerted efforts in recent months to improve ties with Washington under President Trump.
In June this year, Asim Munir met Trump for a private lunch at the White House and later attended a key US military ceremony in Florida. The visit came just weeks after Operation Sindoor. Pakistan credited Trump for helping broker the May 2025 ceasefire with India, though New Delhi denied the claim firmly.