49ers vs Rams live updates: Score, highlights, predictions, analysis

The San Francisco 49ers on Thursday evening open their 2026 regular season schedule vs. the Los Angeles Rams at the Melbourne Cricket Ground in Melbourne, Australia. Typically Week 1 results are mixed and don't play a huge role as the season rolls along. However, Thursday's game feels particularly b

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What is the story about?

The San Francisco 49ers on Thursday evening open their 2026 regular season schedule vs. the Los Angeles Rams at the Melbourne Cricket Ground in Melbourne, Australia.

Typically Week 1 results are mixed and don't play a huge role as the season rolls along. However, Thursday's game feels particularly big with the Rams entering the season as the overwhelming Super Bowl favorites and the 49ers looking to climb back into Super Bowl contention. Thursday's game won't decide anything, but it will determine whether the 49ers whether San Francisco will be looking to fend off the Rams early in the season or if they'll be immediately looking up at them in the standings.

Follow along for highlights, injury news, key plays and instant breakdown as the 49ers

take on the Rams in a pivotal NFC West showdown: