The San Francisco 49ers should be rested after their bye week and ready to return for the stretch run of their 2026 campaign, which begins with an interconference battle against the Las Vegas Raiders on Sunday at Levi's Stadium.
Las Vegas won their first three games of the season, but lost four in a row before outdueling the New York Jets 38-33 on Sunday to even their record at 4-4 on the year.
For this upcoming matchup, the 49ers have opened as 9.5-point favorites, according to BetMGM. They're also -450 on the money line (a $450 bet wins $100) while the over/under is set at 51.5 points.
San Francisco has been hit by the injury bug again this year, but after the week off, they could get some key players back in time to make a push for the top spot
in the NFC playoff picture.
More 49ers: 2 Ravens injuries could spark trade for 49ers QB
This article originally appeared on Niners Wire: 49ers open as two-score favorites for interconference battle in Week 9
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