The Detroit Lions (1-0) look to spoil the grand opening of the new Highmark Stadium on Thursday night as they travel to battle the Buffalo Bills (1-0).
Detroit opened with a 31-30 overtime win against the New Orleans Saints from Ford Field. Meanwhile, the Bills went on the road and dispatched of the Houston Texans, 36-31.
Thursday night's matchup features two of the NFL's high-flying offenses and a laundry list of stars. Detroit running back Jahmyr Gibbs was featured in a major way in the Lions' opener, carrying 29 times for 156 yards and a pair of scores. Lions receiver Amon-Ra St. Brown caught 10 passes for 67 yards and two touchdowns.
As kickoff nears, follow along with Lions Wire for real-time updates, scoring plays, turning points, and expert
analysis throughout Detroit at Buffalo on "Thursday Night Football":
Refresh for the latest Lions-Bills updates once the game starts
Where to watch Lions vs. Bills
07:12 PM ET, September 17 2026, Josh HelmerWatch Lions vs. Bills
- Live stream: Amazon Prime Video
- Time: 8:15 p.m. ET
This article originally appeared on Lions Wire: Lions vs Bills live updates: Score, highlights, predictions, analysis
Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.
