The Detroit Lions (2-2) are eyeing a bounce-back performance after falling on "Sunday Night Football" at the Carolina Panthers (2-2), 32-26.
The Lions' defense--and particularly Detroit's secondary--really struggled once more. Panthers quarterback Bryce Young threw for 329 yards and two scores. Second-year receiver Tetairoa McMillan erupted for a career-high 192 yards and two touchdowns.
Carolina running back Chuba Hubbard also ran for 122 yards and two scores.
Meanwhile, the Lions' offense put up 26 points and 452 yards of offense, but it was the first time this season that Detroit didn't score 31 points. The Lions also had to settle for four field goals, and Detroit and Jared Goff couldn't deliver on a potential game-winning drive.
Still, even
after its latest defensive disappointment, the Lions open as favorites in Week 5 as they head to State Farm Stadium to face the Arizona Cardinals (1-3).
Here's a look at the opening betting odds:
Detroit Lions at Arizona Cardinals opening Week 5 betting odds
The Lions are searching for their first road victory of the season as they battle the Cardinals.
Goff is currently second in the NFL in passing, having completed 67.7% of his passes for 1,214 yards. The 31-year-old has nine touchdown passes and no interceptions thus far this season.
Detroit has won its past three meetings against Arizona and is 5-0-1 in the series dating to 2017. That includes the Lions' 20-13 win in Week 3 of 2024.
Goff threw a pair of touchdown passes in that 2024 game, one to Amon-Ra St. Brown and another to Jahmyr Gibbs.
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This article originally appeared on Lions Wire: Detroit Lions vs Arizona Cardinals opening Week 5 betting odds
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