Patriots vs Bills live updates: Score, highlights, analysis

The New England Patriots will make the trek to the new Highmark Stadium on Sunday for an AFC East showdown with the rival Buffalo Bills. It has been a tale of two completely different teams through the first three weeks of the season. The Patriots have seemingly fallen off a cliff from their improba

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What is the story about?

The New England Patriots will make the trek to the new Highmark Stadium on Sunday for an AFC East showdown with the rival Buffalo Bills.

It has been a tale of two completely different teams through the first three weeks of the season. The Patriots have seemingly fallen off a cliff from their improbable Super Bowl run last season. They got trounced on the road in a 35-6 loss to the Jacksonville Jaguars

last week.

Quarterback Drake Maye has thrown only one touchdown pass with seven turnovers. They are banged up on both sides of the ball, and they'll be without star cornerback Christian Gonzalez and defensive tackle Christian Barmore for this matchup.

Meanwhile, the Bills are a perfect 3-0 after beating the Los Angeles Chargers, Detroit Lions and

Houston Texans.

Get real-time updates, scoring plays, turning points, and expert analysis throughout the Patriots' game against the Bills. Follow along for highlights, injury news, key plays, and instant breakdown as the Patriots take on the Bills in a pivotal AFC conference showdown.

Patriots vs Bills score

Patriots vs Bills injury updates, inactives

09:32 AM ET, October 4 2026, Jordy McElroy

Patriots — OUT: Christian Gonzalez (shoulder); OUT: Christian Barmore (shoulder); QUESTIONABLE: Craig Woodson (shoulder)
Bills — QUESTIONABLE: Christian Benford (toe); QUESTIONABLE: Ray Davis (hamstring); DOUBTFUL: T.J. Sanders (illness)

Patriots vs Bills predictions, betting odds

09:28 AM ET, October 4 2026, Jordy McElroy

Odds via BetMGM.

Patriots 20, Bills 30. The Patriots are dealing with too many injuries, and quite frankly, Bills quarterback Josh Allen is too good to get upset at home in this matchup. Drake Maye has looked like a shell of himself through three games, and the Patriots' defense is missing two of its best players, Christian Gonzalez and Christian Barmore.
Spread: Bills (-7)
Total O/U: 49
Moneyline: Bills (-325)