Week 8 wraps up with a Monday Night Football showdown between NFC East squads in desperate need of a win.
The Dallas Cowboys (2-4) and Philadelphia Eagles (2-4) have both had disappointing starts to the season, and they enter looking to snap recent losing streaks. The Cowboys have dropped their last two to the Buccaneers and Packers. At the same time, the Eagles have lost four in a row as they deal with major injury/availability issues—most notably quarterback Jalen Hurts, who is out for the season after a scary situation involving blood clots in his lungs.
If you are looking for some betting advice for the matchup, we've got you covered. Here are the latest odds from FanDuel.
Eagles vs. Cowboys game odds:
All NFL odds via FanDuel
- Spread: Dallas -4.5 (-108), Philadelphia +4.5 (-112)
- Money Line: Dallas -220, Philadelphia +184
- Over-Under: Over 43.5 (-120), Under 43.5 (-102)
Eagles vs. Cowboys injury report:
🔑 #Cowboys final injury report vs. Eagles:
🚨 Cobie Durant and DeMarvion Overshown are back. 📝 Marist Liufau, PJ Locke are still on IR at the moment but both listed as questionable after FULL practice participation — so they have a chance for Philly. full report below: pic.twitter.com/bcjRGHgmps
— Patrik [No C] Walker (@VoiceOfTheStar) October 24, 2026
Eagles vs. Cowboys prediction, pick:
It seems the Eagles will be starting Tanner McKee at quarterback for the rest of the way, but they are hoping they can get a bit healthier without him this week. Saquon Barkley, listed as questionable, is trending toward playing. However, Devonta Smith is out at receiver once again, as is linebacker Nolan Smith Jr. Two more defensive players, Jalyx Hunt and Jonathan Greenard, are also questionable.
It's hard to have much confidence in Philly given these injuries, though if anyone could allow a McKee-led offense to score some points, it's this Cowboys defense. It remains arguably the worst in the league this season and is putrid against the pass.
The problem for the Eagles is that the Cowboys' offense is still dangerous, and they could be missing a few contributors on that side of the ball. I like the road favorites to win and cover here.
Prediction: Cowboys 27, Eagles 17
Best Bet: Cowboys -4.5
Eagles vs. Cowboys channel, start time, streaming:
Time: 8:15 p.m. ET
TV: ESPN/ABC
This article originally appeared on For The Win: Eagles vs. Cowboys: Week 7 NFL betting odds, prediction, pick
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