The Chargers have released their injury report for Friday ahead of Week 1, and they will be without cornerback Deane Leonard.
Los Angeles ruled Leonard out for Sunday due to an abdominal injury. The Chargers also listed edge rusher Tuli Tuipulotu as questionable due to a hip injury.
Chargers game status:
— Kris Rhim (@krisrhim1) September 11, 2026
CB Deane Leonard (abdomen) is OUT
OLB Tuli Tuipulotu (hip) is questionable
S RJ Mickens (ankle), Brenen Thompson (hip) and Keaton Mitchell (hamstring) are off the report and good for Sunday.
Safety RJ Mickens, wide receiver Brenen Thompson and running back Keaton Mitchell are off the injury report and are good to go against the Cardinals.
Tuipulotu was limited during Wednesday and Thursday practices, and as of Friday, he is officially listed as questionable.
Jim Harbaugh was asked about Tuipulotu’s hip, and he said he wasn't sure when he suffered the injury.
Tuipulotu, 23, is set to enter his fourth season in the league and has established himself as one of the better edge rushers in the NFL. If Tuipulotu were to miss Week 1, rookie edge rusher Akheem Mesidor will see an expanded role against the Cardinals.
As for Leonard, he is set to enter his fifth season in the league, all with the Chargers. Health has not been an issue on his side since his rookie season. Over the last three seasons, Leonard has been held to 29 games, playing only eight in 2025.
Even when Leonard was playing in 2025, he recorded only five tackles.
This article originally appeared on Chargers Wire: Chargers Friday injury report: Who's in, who's out in Week 1?
