The Los Angeles Rams fell to 2-3 on the year Monday night with their heartbreaking overtime loss to the Buffalo Bills. They head into their first meeting with the Arizona Cardinals this week only one game ahead of the division's basement dwellers, but the oddsmakers still view Los Angeles as the heavy favorite.
According to BetMGM, the Rams are 13-point favorites over the Cardinals in Week 6, which is by far the biggest spread of any game this week. The next closest is Kansas City, which is an eight-point favorite over the Chargers.
The over/under sits at 52.5 points, with the Rams being -900 on the moneyline ($900 bet wins $100).
Rams vs. Cardinals odds
- Money line: Cardinals +560 | Rams -900
- Spread: Cardinals +13 (-110) | Rams -13 (-110)
- Over/under: 52.5 (O: -108 | U: -110)
The Rams have owned the Cardinals under Sean McVay, going 16-3 in their 19 meetings the last nine seasons, including
a playoff win by Los Angeles. The Rams swept the Cardinals last season, winning their two games by a combined 45 points.
Arizona comes into this one sitting at 1-4 following a lopsided 45-21 loss to the Detroit Lions in Week 5. The Cards started the year with a shocking win over the Chargers in Week 1 but have now lost four straight, three of which were by double digits.
Kickoff for the Rams-Cardinals game is at 4:05 p.m. ET from SoFi Stadium.
This article originally appeared on Rams Wire: Rams open as massive favorites vs. Cardinals in Week 6
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