Florida State's sixth game of the season is against the Louisville Cardinals. The Seminoles and Cardinals have faced off before, but what is the full series history between these two? Here's the full breakdown.
Florida State's record vs. Louisville is 18-6, as they haven't met since 2023's ACC Championship. In their last appearance, the Seminoles defeated the Cardinals 16-6. In Louisville's last game against FSU, Jack Plummer threw for 111 yards, no touchdowns, and an interception. On the other hand, Brock Glenn passed for 55 yards, no touchdowns, and no picks in relief of Tate Rodemaker and Jordan Travis.
Other Statistics
- Largest margin of victory: FSU 59, Louisville 0 (1953)
- Smallest margin of victory: FSU 9, Louisville 7 (1970)
- Streak: FSU, 2
The Seminoles have a positive record against ACC teams since joining the conference in 1991 after being independent in football for 40 years.
Per StatMuse, Florida State is 226-87-2 against the ACC. They average 31.7 points per game when facing an ACC team and have a strong record against most of their conference opponents.
In 2025, FSU would go on to finish 5-7 and would not make a bowl appearance. Louisville would win the Boca Raton Bowl over Toledo, 27-22.
FSU will look to get its first win on the road since 2023 and move to 4-2 this season when they travel to The Derby City for a match on Oct. 9. Fans can catch the game at 7 p.m. ET on ESPN.
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This article originally appeared on FSU Wire: What's the series history between FSU and Louisville?










