The Buffalo Bills move forward in the 2026 NFL season with a matchup against the New York Jets on the road with a 1 p.m. kickoff on Sunday from MetLife Stadium.
The Bills offense will play its part, as always.
While game plans, coaching, and strategy will play a role, sometimes a big emphasis will sit with some individual players. In terms of the Bills offense, who could those be?
Here are Bills Wire's three potential X-factors on the Bills (7-1) offense against the Jets (2-7) in Week 10:
RB James Cook
At the top, the Bills always look better on offense when both quarterback Josh Allen and running back James Cook contribute. It's a hard duo to stop.
In this contest specifically, the Jets have allowed 128.0 yards per game on the ground this season and have particularly
poor at it in recent weeks. That could mean a big outing for Cook down in the New York.
OL Spencer Brown
The Bills cannot afford to overlook rookie pass rusher David Bailey. Bailey was the second-overall selection by the Jets at the 2026 NFL Draft and has proven himself worthy of that. Bailey has 7.5 sacks.
In addition, the Jets are welcoming edge defender Joseph Ossai back to the lineup on Sunday.
Brown has been limited in practice this week because of an ankle injury. Regardless of who is across from him, Brown has to battle through any bumps and bruises.
WR Khalil Shakir
Simply put, Shakir has a great opportunity to win his matchup against the Jets. Shakir has also been heating up in recent weeks since wide receiver DJ Moore returned to the Bills lineup.
Shakir will likely face D'Angelo Ponds plenty on Sunday. The second-round rookie slot cornerback has struggled this year. Pro Football Focus grades him a brutal 29.3 overall mark so far this season.
Allen would be smart to look Shakir's way often.
This article originally appeared on Bills Wire: 3 potential X-factors on the Bills offense at Jets in Week 10
