The Arizona Cardinals are on the road against the Seattle Seahawks and are giving Gardner Minshew his first start this season. Minshew replaced Jacoby Brissett last week in the Cardinals' 33-30 overtime win and threw three touchdown passes, rallying the team from 14 points down. Brissett was benched and then traded this past week.
They face a Seattle Seahawks team missing Sam Darnold, Rashid Shaheed, Leonard Williams and two starting offensive linemen. The Seahawks are coming off a loss on Monday night, but have beaten the Cardinals in 10 straight meetings.
It is Gardner Minshew vs. Drew Lock in Week 9.
Can the Cardinals get the upset?
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Cardinals vs. Seahawks score
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Cardinals vs. Seahawks picks, predictions
02:41 PM ET, November 8 2026, Jess RootI’m intrigued with what the offense will look like with a full game of Minshew, and the number of players out for Seattle gives Arizona a chance, but I don’t trust the Cardinals’ defense, while the Seattle defense is still great. Allgeier won’t have the same game he had, so the offense will struggle more. Seahawks 24, Cardinals 13
Betting picks (BetMGM)
- Moneyline: Seahawks -425
- Spread: Seahawks -8.5
- Total: Under 39.5
Cardinals vs. Seahawks TV, kickoff
02:39 PM ET, November 8 2026, Jess RootWhat: Arizona Cardinals at Seattle Seahawks
Where: Lumen Field, Seattle, WA
When: 4:25 p.m. ET (2:25 p.m. Arizona time
TV: FOX
Broadcasters: Kenny Albert, Jonathan Vilma, Megan Olivi (sideline reporter)
This article originally appeared on Cards Wire: Cardinals vs. Seahawks live updates: Score, highlights, predictions, analysis
