The Arizona Cardinals will face the San Francisco 49ers on Sunday on the road. They have not had a ton of recent success against the 49ers. They lost to them in both meetings last season and are 2-6 in their last eight against them.
The 49ers lead the all-time series 38-31.
The Cardinals had an 8-0 run from 2015-2018, but the Niners have won nine of the last 14 meetings since.
49ers starting quarterback Brock Purdy is 5-1 in six starts against the Cardinals in his career. Backup Mac Jones beat them last season. The only other recent win by the Cardinals was a 2024 win when Joshua Dobbs started for the 49ers.
For first-year head coach Mike LaFleur, he gets to coach against his mentor, Kyler Shanahan, for whom he worked as an assistant with the 49ers
from 2017-2020.
The Cardinals have lost three of their last 4 meetings on the road against the 49ers but are 6-5 at Levi's Stadium since it opened in 2014.
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This article originally appeared on Cards Wire: Cardinals vs. 49ers history: Arizona struggling in recent meetings
