The Cowboys and Chippewas have had similar fates so far during the 2026 college football season. Both teams lost in blowout fashion during their first contest, and won their second game of the year in tilts that came down to the wire.
The spread indicates that Wyoming and Central Michigan are destined to play another close game here in Week 3, and in such a closely contested game, the end result might come down to who protects the football best.
If you are looking for some betting advice for the matchup, we've got you covered. Here are the latest odds for the game, courtesy of BetMGM.
Wyoming vs. Central Michigan game odds
All college football odds via BetMGM
- Spread: Wyoming +1.5 (-110), Central Michigan -1.5 (-110)
- Money Line: Wyoming +100, Central Michigan -120
- Over-Under: Over 39.5 (-110), Under 39.5 (-110)
Wyoming vs. Central Michigan prediction, pick:
The Chippewas may have been fortunate to defeat Colgate last week, as the 13-10 victory was a sloppy affair. Central Michigan
quarterbacks threw two interceptions, and the team also lost a fumble.
Things weren't a whole lot better for Wyoming, who lost two fumbles in their 21-13 victory over Northern Colorado in Week 2.
It's a football cliche, but the team that doesn't beat themselves will win this game. Given Matt Drinkall's slight edge as Central Michigan head coach in his second season over a struggling Jay Sawvel in year three, expect Central Michigan to do just enough to squeak out another win.
Prediction: Central Michigan 20, Wyoming 17
Best Bet: Central Michigan -1.5
Wyoming vs. Central Michigan, start time, streaming:
Time: 1:00 p.m. ET
Stream: ESPN+
Watch Wyoming vs. Central Michigan on ESPN+
Get more betting analysis and predictions at Sportsbook Wire.
Contact/Follow @College_Wire on X and @College_Wires on Threads. Like our page onFacebook to follow ongoing coverage of college sports news, notes, and opinions.
This article originally appeared on College Sports Wire: Wyoming vs. Central Michigan: Week 3 Betting Odds, Prediction
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.
