Week 3 of the NFL has some intriguing matchups, including division winners from 2025 meeting on Sunday night and Monday night.
The Chicago Bears will be without Caleb Williams and Case Keenum could make his first regular-season game appearance since 2023 as the starter against the Philadelphia Eagles on Sunday.
A night later, the Los Angeles Rams will visit the Denver Broncos as Matthew Stafford will test the elite Denver defense, including DB Patrick Surtain II.
The New York Jets-Detroit Lions game and the Tennessee Titans-New York Giants contest will see coaches return to their former haunts.
Aaron Glenn was the Lions' defensive coordinator before moving to MetLife Stadium as the Jets' head coach.
At MetLife on Sunday, former Jets head coach Robert
Saleh and former Giants head coach Brian Daboll will be the visitors as the Titans take on Big Blue.
The quarterback matchup pits two former No. 1 overall picks. Cam Ward and the Titans have struggled in his first year-plus. For the Giants, Jameis Winston, once a No. 1 overall pick by the Tampa Bay Buccaneers, takes over the starting duties for the injured Jaxson Dart.
Speaking of the Buccaneers, their game with the Minnesota Vikings will not only feature former No. 1 draft picks at quarterback but both won the Heisman Trophy at the same school, Oklahoma.
Kyler Murray returns from a concussion to start for the Vikings and Baker Mayfield will be the QB for the winless Buccaneers.
Mayfield was the No. 1 pick by the Cleveland Browns in 2018 and Murray went first overall to the Arizona Cardinals the following year.
A kind of quirky quarterback coincidence of sorts happens in the Las Vegas-New Orleans game. Raiders starting quarterback Kirk Cousins was a fourth-round pick by Washington in 2012, the same year current Saints coach Kellen Moore went undrafted before signing with the Detroit Lions.
Cousins has had a long career. Moore played in three games in 2015 for the Cowboys.
This article originally appeared on Touchdown Wire: NFL Week 3 storylines feature QB shifts and reunions
