The Detroit Pistons (4-1) and Brooklyn Nets (0-4) meet Friday for an Eastern Conference clash. Tip from Barclays Center in Brooklyn, New York, is set for 7:30 p.m. ET. Let's analyze NBA odds around the Pistons vs. Nets odds and make our expert NBA picks and predictions for the best bets.
2025-26 season series: Pistons won 3-1, including 2 wins in Brooklyn
The Pistons beat the Charlotte Hornets 97-89 Wednesday, covering as a 7.5-point home favorite with the Under (212.5) cashing. Detroit was led by G Cade Cunningham's 30 points on 10 of 22 shooting. He added 5 rebounds and 7 assists. The Pistons have yet to allow more than 113 points in a game and are 4-1 against the spread (ATS).
The Nets lost to the Boston Celtics 125-124 in overtime Tuesday,
covering as a 13.5-point road underdog as the Over (223.5) hit with ease. F Michael Porter Jr. led the Nets with 27 points. The Nets and Sacramento Kings are the only teams without a win. The Nets are 2-2 ATS.
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Pistons at Nets odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:01 a.m. ET.
- Moneyline (ML): Pistons -295 (bet $295 to win $100) | Nets +230 (bet $100 to win $230)
- Against the spread (ATS): Pistons -7.5 (-110) | Nets +7.5 (-110)
- Over/Under (O/U): 222.5 (O: -110 | U: -110)
Pistons at Nets key injuries
Pistons
- C Jalen Duren (hamstring) out
- F Isaiah Joe (hip) questionable
Nets
- G Egor Demin (bone) out
For most recent updates: Official NBA injury report.
Pistons at Nets picks and predictions
Prediction
Pistons 111, Nets 106
Moneyline
PASS.
Avoid this play. The Pistons (-295) should come out on top at home, but are too expensive to consider to win outright.
Against the spread
BET NETS +7.5 (-110).
The Nets have somehow managed to keep games close on the road. They are 2-0 ATS away from home, having lost by 1 to the Celtics and 4 to the Cleveland Cavaliers. Brooklyn closed as a double-digit underdog in both those outings. Behind F Julius Randle (22.5 points per game) and Porter Jr. (22.8 PPG), they have the veteran talent to keep this game close.
The Pistons offense has hit a wall, and the absence of Duren isn't going to help. Detroit has scored 97 points in 2 straight games and 106 points or fewer in 3 straight. It has closed as a favorite of 7.5 or more points just once and won that game by 8.
Expect a close game and back NETS +7.5 (-110).
Over/Under
BET UNDER 222.5 (-110).
There's no reason to think this is going to be a high-tempo game. The Pistons rank last in the NBA in pace, and they should force the Nets to play their style. Detroit has gone Under in 3 straight games.
The Nets have topped 109 points in 2 of 4 outings this season. They sit 23rd in offensive rating, so the Nets offense has struggled to be efficient and should have issues scoring consistently, given the likelihood this game is played at an ultra-slow pace.
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This article originally appeared on Sportsbook Wire: Detroit Pistons at Brooklyn Nets odds, picks and predictions
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