The Toronto Blue Jays (77-79) and Baltimore Orioles (75-81) meet Monday to commence a 3-game series. First pitch from Oriole Park at Camden Yards in Baltimore, Maryland, is set for 6:35 p.m. ET. Let's analyze MLB odds around the Blue Jays vs. Orioles odds and make our expert MLB picks and predictions for the best bets.
Season series: Blue Jays lead 6-4
The Blue Jays beat the Texas Rangers 7-2 on Sunday, closing as a +145 underdog with the Over (7.5) cashing. Toronto has lost 4 of its last 6 games and is just 5-8 since Sept. 6. While the postseason is still possible, the Blue Jays are on the outside looking in, 3 games behind the Chicago White Sox for the final AL Wild Card spot.
The Orioles were swept by the Milwaukee Brewers in their last series,
dropping the finale 3-0 Sunday. They closed as a +180 underdog and the Under (7.5) hit. Baltimore has had an atrocious September, going 6-12 so far. The Orioles sit 5 games back of the White Sox for the final AL Wild Card spot.
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Blue Jays at Orioles projected starters
RHP Trey Yesavage vs. RHP Shane Baz
Yesavage (5-5, 3.65 ERA) makes his 19th start. He has a 1.14 WHIP, 4.4 BB/9 and 8.7 K/9 through 93 2/3 innings.
- Last start: No-decision, 2 IP, 0 ER, 0 H, 1 BB, 0 K in a 7-2 road loss vs. Houston Astros on Aug. 4
- Career vs. Orioles: 0-1, 5.91 ERA (10 2/3 IP, 7 ER), 1.50 WHIP, 7.6 K/9 in 2 starts
- 2026 road splits: 2-2, 3.14 ERA (48 2/3 IP, 17 ER), 1.15 WHIP, 5 HR, 27 BB, 51 K in 10 starts
Baz (6-15, 4.11 ERA) makes his 31st start. He has a 1.35 WHIP, 3.1 BB/9 and 7.9 K/9 through 173 innings.
- Last start: No-decision, 4 IP, 3 ER, 7 H, 2 BB, 2 K in a 7-5 road victory vs. New York Mets Tuesday
- Career vs. Blue Jays: 4-1, 2.13 ERA (38 IP, 9 ER), 1.05 WHIP, 8.3 K/9 in 7 starts
- 2026 home splits: 4-7, 3.92 ERA (85 IP, 37 ER), 1.38 WHIP, 7 HR, 28 BB, 77 K in 15 starts
Blue Jays at Orioles odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated 10 a.m. ET.
- Moneyline (ML): Blue Jays -110 (bet $110 to win $100) | Orioles -110 (bet $110 to win $100)
- Run line (RL)/Against the spread (ATS): Blue Jays -1.5 (+155) | Orioles +1.5 (-190)
- Over/Under (O/U): 7.5 (O: -105 | U: -115)
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Blue Jays at Orioles picks and predictions
Prediction
Blue Jays 5, Orioles 3
Moneyline
BET BLUE JAYS (-110).
The Blue Jays are in must-win mode, and their offense has been consistent enough to trust. They've scored 5 runs or more in 5 of their last 8 games, and they should have the pitching advantage with the return of Yesavage, who has been out nearly 7 months with a meniscus tear.
The Orioles have generated no offense and are in freefall mode. They've scored 0 runs in their last 18 innings and have tallied 3 runs or fewer in 5 of their last 8 games. Baz leads the league in losses and Baltimore is just 3-8 in his last 11 starts. Take the side with more on the line and back BLUE JAYS (-105).
Run line/Against the spread
PASS.
There's not a ton of great value here. The Blue Jays (+155) are the run-line favorite, but they are better played to win outright. The Orioles (-190) are too expensive as the underdog here.
Over/Under
BET OVER 7.5 (-115).
Both teams are trending toward the Over here, and it's worth taking.
The Orioles are 8-4 O/U in their previous 12 games and have gone Over in Baz's last 2 starts. The Blue Jays are 8-1 O/U across their previous 9 outings and have allowed at least 6 runs in 5 of those.
Best prop bet
Blue Jays SP TREY YESAVAGE OVER 3.5 STRIKEOUTS (+125)
Yesavage has gone north of this total in 3 of his last 4 starts. While he's coming off an injury, even if he gets to 4 innings, there's a good chance he's able to top his total given his 8.7 K/9 average this season. Baltimore has been struck out the third-most times of any team this season.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Toronto Blue Jays at Baltimore Orioles odds, picks and predictions
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