The Monday Night Football game in Week 9 pits the Buffalo Bills (6-1) against the Minnesota Vikings (6-1). Kickoff from U.S. Bank Stadium in Minneapolis, Minnesota, is at 8:15 p.m. ET (ESPN / ABC). Let's analyze NFL prop bet odds around the Bills vs. Vikings and tab the 5 best prop bets to go along with Sportsbook Wire's expert NFL picks and predictions for Week 9.
The Bills won their third-straight game last week against a shorthanded Baltimore Ravens team 36-10 final. Third-string QB Joe Fagnano began his NFL career as Lamar Jackson and Tyler Huntley both were injured in the contest. Buffalo covered as a -3.5 favorite while the Under (54.5) hit. QB Josh Allen was 21 of 34 passing with 289 yards, 3 total TDs and an interception. RB James Cook
had 101 scrimmage yards and a TD.
The Vikings are fresh off their first loss of 2026 in a 19-15 defeat against the Detroit Lions. The Vikings failed to cover as a 3.5-point underdog and the Under (45.5) landed. All sights in Minnesota quickly looked forward from that outing because of injury. Starting QB Kyler Murray (hamstring) is out and backup Carson Wentz will get the nod.
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Best Bills at Vikings prop bets
Odds provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Last updated Sunday at 11:41 p.m. ET.
Vikings WR JUSTIN JEFFERSON ANYTIME TD (+160)
Wentz starting over Murray might actually be a blessing in disguise. He will likely hang around in the pocket more than Murray would against the Bills' secondary that leaves a lot to be desired this year. Not to mention, against the Green Bay Packers earlier this season, Wentz and Jefferson connected for 2 TDs.
Bills QB JOSH ALLEN ANYTIME TD (-120)
No offense to the Vikings defense, it is inevitable. There is only 1 game this year Allen did not find the end zone himself. Allen is unstoppable at the goal line.
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Bills RB JAMES COOK OVER 95.5 RUSH + RECEIVING YARDS (-113)
Whether it's strictly on the ground or there is a healthy mix of quick passes involved for Cook, he has to contribute one way or another for the Bills to have a chance and Buffalo knows that. The Bills do not sport a heavy hitter in the passing game to beat the Vikings' No. 1 ranked pass defense (154.9 yards per game). Minnesota is 17th against the run (116.7 YPG) and the Bills will attack that.
Vikings QB CARSON WENTZ OVER 209.5 PASSING YARDS (-113)
Wentz is a backup and it appears that tag is weighing heavy on the total for Wentz. If you exclude the Ravens' third-string QB in Fagnano last week, every quarterback that has faced Buffalo this season has surpassed this total. Wentz is far more experienced.
Bills QB JOSH ALLEN OVER 0.5 INTERCEPTIONS (-114)
The Vikings have averaged at least 1 INT per game this season, with 8 total in 7 games played. For as good as Allen is, he has 5 interceptions in his past 5 games. He's good for a weekly "hero ball" or two that Minnesota's secondary will jump on.
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This article originally appeared on Sportsbook Wire: Buffalo Bills at Minnesota Vikings best prop bets for Monday Night Football
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