The Philadelphia Flyers (2-6-3) face the Buffalo Sabres (4-3-2) Wednesday at KeyBank Center in Buffalo, New York. Puck drop is set for 7:30 p.m. ET (TNT). Let's analyze NHL odds around the Flyers vs. Sabres odds and make our expert NHL picks and predictions.
2025-26 season series: 1-1 split, with the home team winning both games
The Flyers have gotten off to a slow start this season and have yet to win a game on the road, going 0-4-1 away from home. However, after going winless in 9 games to begin the year, Philadelphia has won back-to-back outings. After beating the Ottawa Senators in a 3-1 final Saturday, the Flyers followed that up with a surprising win against the Western Conference powerhouse Colorado Avalanche in a 3-2 contest Monday. F Matvei
Michkov (6 goals, 1 assist) scored twice against the Avs.
The young Sabres have just finished a road trip to Canada which saw all 3 games go into extra time. Buffalo only won 1 of the 3, but claimed 4 of 6 possible points in a positive trip up north. The trip also saw G Ukko-Pekka Luukkonen (3.59 GGA, .860 SP) make a claim for the No. 1 job between the pipes moving forward.
F Tage Thompson (5 goals, 4 assists) leads the Sabres on the score sheet early on this season and Buffalo is expecting D Rasmus Dahlin (back) to return from injury in this game.
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Flyers at Sabres odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday 11:38 p.m.
- Moneyline (ML): Flyers +150 (bet $100 to win $150) | Sabres -185 (bet $185 to win $100)
- Puck line (PL)/Against the spread (ATS): Flyers +1.5 (-160) | Sabres -1.5 (+135)
- Over/Under (O/U): 6 (O: +110 | U: -110)
Flyers at Sabres projected goalies
Joseph Woll (4-2-0, 2.53 GAA, .886 SV%) vs. Ukko-Pekka Luukkonen (3-2-2, 3.59 GGA, .860 SV%)
Woll was between the pipe for the Flyers' last win against the Avs. In his last 5 games, Woll has allowed more than two goals in regulation just once, a 4-1 loss to the Carolina Hurricanes Oct. 11.
Luukkonen played strong in 2 games against the Montreal Canadiens and one against the Toronto Maple Leafs during the Sabres' quick road trip to Canada. Both losses required either a shootout or overtime effort from the opposing team. Luukkonen is 1-1 on home ice this season.
Lightning at Golden Knights picks and predictions
Prediction
Sabres 4, Flyers 3
Moneyline
PASS.
The Sabres do not have enough juice to play at -185.
Puck line/Against the spread
BET FLYERS +1.5 (-160).
You might sweat out the empty netter at the end, but the Flyers are starting to heat up taking the spread feels safe after the momentum built after Philadelphia's win over Colorado. The Sabres have still played well recently and Buffalo will get Dahlin back in the lineup, their captain, so they are the pick to win. You could roll the dice on a Flyers win for a nicd return. Philadelphia is also 6-5 ATS this season despite the team's record.
Over/Under
We have 2 teams in opposite sides of the ledger here as the Sabres are 6-3 against the total while the Flyers are 2-9. With this one being in Buffalo, lean toward the game going the Sabres' way in this department.
I'll go OVER 6 (-110).
Best prop bet
Philadelphia F MATVEI MICHKOV ANYTIME GOAL (+235).
This is a really good number for a player who has scored in 3 straight games, burying 5 total in that time frame.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Philadelphia Flyers at Buffalo Sabres odds, picks and predictions
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