The Portland Trail Blazers (4-1) and Denver Nuggets (3-2) meet Monday at Ball Arena in Denver, Colorado. Tip-off is set for 9 p.m. ET. Let's analyze NBA odds around the Trail Blazers vs. Nuggets odds and make our expert NBA picks and predictions for the best bets.
2025-26 season series: Nuggets won 3-1, including NBA Cup
Portland handed the Utah Jazz a 112-90 loss on Halloween while covering as a 6.5-point road favorite as the Under (233.5) cashed. F Deni Avdija and G Damian Lillard combined for 46 points, but the Blazers won that game because they dominated 48-37 on the glass and hit 16 3-pointers. The Blazers continue to be among the best in both aspects offensively, sitting top-3 in both 3-point makes and attempts and top-7 in rebounds per
game.
Denver beat the Phoenix Suns 127-120 Friday to cover as a 4.5-point road favorite while the Over (231.5) hit. G Jamal Murray went off for 39 points, and G Christian Braun put up 31 points on 7 of 9 shooting from deep. Murray has been the leading scorer in all of Denver's wins this season, while C Nikola Jokic (21.9 points, 9.8 rebounds, 9.2 assists per game) has yet to lead the team in scoring in any contest this season.
Watch the NBA on Fubo!
Trail Blazers at Nuggets odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:54 a.m. ET.
- Moneyline (ML): Trail Blazers +145 (bet $100 to win $145) | Nuggets -175 (bet $175 to win $100)
- Against the spread (ATS): Trail Blazers +4.5 (-115) | Nuggets -4.5 (-105)
- Over/Under (O/U): 231.5 (O: -110 | U: -110)
Trail Blazers at Nuggets key injuries
Trail Blazers
- G Ja Morant (hamstring) out
- G Shaedon Sharpe (knee) out
Nuggets
- G Alpha Diallo (wrist) questionable
- F Spencer Jones (hamstring) out
- G Julian Strawther (knee) out
For most recent updates: Official NBA injury report.
Trail Blazers at Nuggets picks and predictions
Prediction
Trail Blazers 128, Nuggets 126
Moneyline
BET TRAIL BLAZERS (+145).
Portland has simply been the better team than Denver this season. The Blazers are top-6 in both defensive and offensive rating while being a very good shooting and rebounding team. The Nuggets, on the otherhand, are in the middle of the pack offensively and have a bottom-10 defense. The Blazers also match up well against Denver, they have big bodies down low to throw at Jokic and longer bodies to throw on Murray, so expect that Portland looks better than Denver and comes away with the win here.
Against the spread
PASS.
Portland will cover here as +4.5 (-115) underdogs, but they are not worth paying the extra juice to back here when I am picking the Blazers to win outright. Bet the moneyline and/or total for the much higher potential payout.
If you aren't confident in Portland given that Morant is out, then back the Blazers here rather than on the ML.
Over/Under
BET OVER 232.5 (-110).
Portland's defense is much better than Denver's, but the Blazers have still allowed over 120 points in 3 of 5 games, so it is likely that both teams have a lot going their way offensively in this one. Expect to see the stars from both squads have very good scoring numbers in this matchup.
The Over has hit in 3 of Denver's last 4 games and in 2 of Portland's last 3 road games. The Over has also hit in 9 of the last 10 matchups between these squads, sitting at 3-0 in the last meetings.
Best prop bet
Trail Blazers F DENI AVDIJA OVER 22.5 POINTS (-115).
Deni has been Portland's leading scorer in every game but the season opener, and he has gotten at least 23 points in every game this season but that one as well. Avdija has also scored at least 23 points in 4 of his last 5 matchups against the Nuggets, and he has taken at least 15 shots and 8 free throws in back-to-back matchups against Denver.
Betting odds calculator
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow SportsbookWire on X at SportsBookWire and on Facebook.
Access more NBA coverage:
HoopsHype | Celtics Wire | Lakers Wire | Nets Wire | Rockets Wire | Sixers Wire | Thunder Wire | Warriors Wire | Rookie Wire | List Wire
This article originally appeared on Sportsbook Wire: Portland Trail Blazers at Denver Nuggets odds, picks and predictions
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.
