The TCU Horned Frogs (4-4, 2-3 Big 12) and No. 22 Arizona Wildcats (6-2, 3-2) clash Friday in Tucson, Arizona. Kickoff from Casino del Sol Stadium is at 10:15 p.m. ET (ESPN). Let's analyze college football odds around the TCU vs. Arizona odds and make our expert college football picks and predictions for the best bets.
The Horned Frogs have won 2 of their last 3 games and beat the Kansas Jayhawks 22-16 at home Saturday as 6.5-point favorites with the Under (45.5) cashing, coming back from a 13-0 halftime deficit. QB Jaden Craig had a 17-yard go-ahead TD run with 1:11 to go.
The Wildcats, who are No. 22 in the College Football Playoff rankings, had a 5-game winning streak snapped on Saturday, losing 34-26 at the No. 13 Texas Tech Red Raiders as 3.5-point
underdogs with the Over (55.5) cashing. QB Noah Fifita hit 33 of 45 passes for 417 yards and a TD and has thrown 19 TD passes and only 4 INTs in 8 games. Arizona allowed 175 rushing yards and a touchdown to Tech RB J'Koby Williams and 117 to QB Tommy Castellanos.
TCU won the last meeting 49-28 in 2024 and leads the all-time series 2-1.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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TCU at Arizona odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 12:06 a.m. ET.
- Moneyline (ML): TCU +230 (bet $100 to win $230) | Arizona -285 (bet $285 to win $100)
- Against the spread (ATS): TCU +7.5 (-112) | Arizona -7.5 (-105)
- Over/Under (O/U): 46.5 (O: -108 | U: -110)
TCU at Arizona picks and predictions
Prediction
Arizona 26, TCU 20
Moneyline
Arizona has scored less than 34 points only twice this season. Both times came against top-25 teams in Texas Tech and the BYU Cougars. However, TCU hasn't allowed more than 24 points this season, even hanging tough with BYU in a 17-10 loss.
The Wildcats average 324.1 passing yards per game. TCU allows only 174.6 passing yards per game.
TCU has arguably the best defense in the conference. However, Arizona's attack will be too much. Expect Arizona to win, but the spread gives you better value.
Against the spread
Arizona has won by no fewer than 10 points this season. Only once has TCU lost by at least 8 points, and it was by 8 points.
Ultimately, Arizona will win, but TCU's defense will keep it close.
BET TCU +7.5 (-112).
Over/Under
The highest total in TCU's last 6 games has been 44 while half of Arizona's 8 games have stayed under 47 points.
BET UNDER 46.5 (-110).
Betting odds calculator
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This article originally appeared on Sportsbook Wire: TCU Horned Frogs at Arizona Wildcats odds, picks and predictions
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