The Cleveland Cavaliers (6-6) and Miami Heat (5-6) meet Friday in NBA Cup action at Kaseya Center in Miami, Florida. Tip-off is set for 8 p.m. ET. Let's analyze NBA odds around the Cavaliers vs. Heat odds and make our expert NBA picks and predictions for the best bets.
2025-26 season series: Tied 2-2 with each team winning once on road
The Cavs took down the New York Knicks 115-107 Wednesday as 4.5-point road dogs. G James Harden led the way with 32 points on 5 of 7 shooting from downtown. G Donovan Mitchell added 23 points, 7 boards and 6 assists. The Cavs are just 2-4 on the road and will be without F Evan Mobley Friday.
The Heat have won 2 straight after a 115-109 win at the Utah Jazz Tuesday, but failing to cover as 8.5-point favorites. Miami
went 3-2 on the West Coast trip. F Giannis Antetokounmpo had 30 points and 11 boards. C Bam Adebayo struggled, going 1 for 8 from the floor, but finished with 11 points and 8 boards.
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Cavaliers at Heat odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:03 p.m. ET.
- Moneyline (ML): Cavaliers +115 (bet $100 to win $115) | Heat -140 (bet $140 to win $100)
- Against the spread (ATS): Cavaliers +2.5 (-115) | Heat -2.5 (-105)
- Over/Under (O/U): 235.5 (O: -110 | U: -110)
Cavaliers at Heat key injuries
Cavaliers
- G Sam Merrill (elbow) out
- F Evan Mobley (toe) out
Heat
- G Pelle Larsson (illness) questionable
- G Klay Thompson (ankle) questionable
For most recent updates: Official NBA injury report.
Cavaliers at Heat picks and predictions
Prediction
Heat 115, Cavaliers 111
Moneyline
The Heat (-140) at home are the pick with Mobley out. However, they're just 1-3 at home, and I'd rather lay the points. PASS.
Against the spread
Take the HEAT -2.5 (-105). Giannis and Bam should be able to exploit Cleveland's banged-up frontcourt. The lane will be clogged, which will force the Cavs to beat you with 3s.
Over/Under
The Cavs are 6-6 O/U this season, and the Heat are 4-7. This is a tall number, and the Heat have cashed 4 straight Unders.
Go UNDER 235.5 (-110).
BEST PROP BET
Take Heat C BAM ADEBAYO UNDER 9.5 REBOUNDS (-140).
Giannis has been grabbing the bulk of the rebounds of late. Adebayo has 10 boards in just 2 of 11 games thus far.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Cleveland Cavaliers at Miami Heat odds, picks and predictions
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