The Portland Trail Blazers (2-0) and Los Angeles Lakers (3-0) meet Tuesday in Los Angeles, California. Tip-off from Crypto.com Arena is at 11 p.m. ET (Peacock / NBC). Let's analyze NBA odds around the Trail Blazers vs. Lakers odds and make our expert NBA picks and predictions for the best bets.
2025-26 season series: Trail Blazers won 2-1, including a win in L.A.
The Blazers have been off since Friday. After destroying the Phoenix Suns 124-83 in their season opener Wednesday, they beat the Sacramento Kings 128-120 Friday as 9.5-point road favorites with the Over (231.5) cashing. They trailed the whole first half before starting the second half with a 15-0 run. F Deni Avdija led the way with 26 points, 6 rebounds and 6 assists.
The Lakers played
on Monday, beating the Utah Jazz 132-123 as 6.5-point road favorites with the Over (237.5) cashing. G Luka Doncic nearly had a 50-point triple-double, scoring 52 with 10 assists and 8 boards. G Austin Reaves added 29.
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Trail Blazers at Lakers odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:10 a.m. ET.
- Moneyline (ML): Trail Blazers +110 (bet $100 to win $110) | Lakers -135 (bet $135 to win $100)
- Against the spread (ATS): Trail Blazers +2.5 (-115) | Lakers -2.5 (-105)
- Over/Under (O/U): 234.5 (O: -105 | U: -115)
Trail Blazers at Lakers key injuries
Trail Blazers
- C Branden Carlson (concussion) questionable
- G Scoot Henderson (ankle) questionable
- G Shaedon Sharpe (knee) out
Lakers
- G Cameron Carr (oblique) out
- F Adou Thiero (knee) out
For most recent updates: Official NBA injury report.
Trail Blazers at Lakers picks and predictions
Prediction
Lakers 131, Trail Blazers 127
Moneyline
Both teams have scored 124 or more in all their games this season so far. Neither team has lost.
The Blazers have won 3 of the last 4 meetings, after the Lakers had won 6 straight in the series.
Both teams look good, but it is still a small sample size, so we will lean with the home team. Doncic is the best player between both teams and he will make the difference.
If you don't want to fool with the points, BET LAKERS (-135), but the small spread offers a better value.
Against the spread
All 3 wins by the Lakers have been by at least 8 points. The last 10 meetings between the teams have been decided by at least 6 points.
BET LAKERS -2.5 (-110).
Over/Under
This seems easy. Neither team has scored less than 124 points.
The Lakers' last 2 games have cleared the projection for this game, and the Over has cashed in their last 2 games.
BET OVER 234.5 (-105).
Best prop bet
Lakers G AUSTIN REAVES OVER 2.5 3-POINTERS (+120)
Reaves has had at least 3 made 3s in his last 2 games.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Portland Trail Blazers at Los Angeles Lakers odds, picks and predictions
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