The Indiana Pacers (2-6) visit the Memphis Grizzlies (6-1) Wednesday for an 8 p.m. ET tip-off at FedExForum in Memphis, Tennessee. Let's analyze NBA odds around the Pacers vs. Grizzlies odds and make our expert NBA picks and predictions for the best bets.
2025-26 season series: Grizzlies won 2-0
Indiana has dropped 5 games in a row after losing 108-104 against the Atlanta Hawks Monday, covering as a 10.5-point home underdog with the Under (227.5) hitting with ease. The Pacers were plagued with injuries, with no true starter playing and only 6 total players seeing any minutes. C Jay Huff scored a team-high 22 points, while all 6 players who played scored at least 12 points in the loss.
Memphis had a 6-game winning streak snapped with its first loss
of the season Monday, a 135-134 overtime loss against the New Orleans Pelicans as a 5.5-point home favorite with the Over (231.5) hitting. G Ty Jerome led all scorers with 40 points.
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Pacers at Grizzlies odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:10 a.m. ET.
- Moneyline (ML): Pacers +220 (bet $100 to win $220) | Grizzlies -275 (bet $275 to win $100)
- Against the spread (ATS): Pacers +6.5 (-105) | Grizzlies -6.5 (-115)
- Over/Under (O/U): 229.5 (O: -110 | U: -110)
Pacers at Grizzlies key injuries
Pacers
- G Tyrese Haliburton (hamstring) out
- G T.J. McConnell (hamstring) out
- G Kelly Oubre Jr. (calf) questionable
- F Obi Toppin (back) questionable
- C Ivica Zubac (ankle) questionable
Grizzlies
- G Scotty Pippen Jr. (back) out
- C Quinten Post (ankle) questionable
For most recent updates: Official NBA injury report.
Pacers at Grizzlies picks and predictions
Prediction
Grizzlies 115, Pacers 106
Moneyline
PASS.
There is minimal value on the Grizzlies (-275) to beat an ailing Pacers (+220) squad.
Against the spread
BET GRIZZLIES -6.5 (-110).
The Grizzlies are 6-1 both straight up (SU) and ATS this season, covering in 4 of their 5 games as favorites and 2 of their 3 games at home. They have won 2 of their last 3 games by 21 or more points, while dominating teams defensively.
Even with the Pacers set to see a more full lineup Wednesday, they are still without Haliburton, who has left a major hole in the lineup since his injury. The Pacers are 2-3 ATS over their last 5 games, failing to cover in their previous 2 on the road.
Over/Under
BET UNDER 229.5 (-110).
The Pacers have hit the Under in 4 of their last 5 games, including back-to-back. They have scored 109 or fewer points in 5 of their last 7 and will face a Grizzlies' defense that has held their opponents to 105 or fewer in 3 of their last 4.
The Pacers have played competent defense despite their offensive struggles, allowing 114 or fewer in 5 of their last 6.
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This article originally appeared on Sportsbook Wire: Indiana Pacers at Memphis Grizzlies odds, picks and predictions
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