The Cleveland Cavaliers (4-3) and Oklahoma City Thunder (5-2) meet Wednesday at Paycom Center in Oklahoma City, Oklahoma. Tip-off is set for 8 p.m. ET. Let's analyze NBA odds around the Cavaliers vs. Thunder odds and make our expert NBA picks and predictions for the best bets.
Season series: Thunder lead 1-0
OKC won 117-112 in Cleveland Monday as a +4.5 underdog (+145 ML) as the Under (229.5) just held on. Thunder G Shai Gilgeous-Alexander went for 43 points, 8 assists, 3 rebounds, 2 steals and a block with 4 triples, while G Ajay Mitchell was a solid secondary source with 20 points, 5 rebounds and a block. The Cavaliers had 7 players with 10+ points, with G Donovan Mitchell going for 17 points and 11 assists in a losing effort.
Oklahoma City bounced
back nicely after a 119-98 loss last time out in Houston as a 2.5-point underdog as the Under (219.5) cashed. The Under has cashed in 3 in a row, while going 6-1 in the past 7 games.
Cleveland lost its first game of the season at home in 4 tries. On the road, the Cavaliers are 1-2 straight up (SU) in 3 games, while going 1-2 against the spread (ATS). It covered in the most recent road game, 136-111, in Milwaukee as an 8.5-point favorite as the Over (235.5). The Under is 3-1 in the past 4 outings.
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Cavaliers at Thunder odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:18 a.m. ET.
- Moneyline (ML): Cavaliers +115 (bet $115 to win $100) | Thunder -140 (bet $140 to win $100)
- Against the spread (ATS): Cavaliers +2.5 (-115) | Thunder -2.5 (-105)
- Over/Under (O/U): 227.5 (O: -115 | U: -105)
Cavaliers at Thunder key injuries
Cavaliers
- F Nae'Qwan Tomlin (back) out
- G Jaylon Tyson (ankle) out
- F Peyton Watson (hamstring) out
Thunder
- C Chet Holmgren (knee) out
- C Thomas Sorber (knee) out
- G Nikola Topic (back) out
- G Cason Wallace (shoulder) out
- G Jalen Williams (ankle) out
- F Jaylin Williams (back) questionable
For most recent updates: Official NBA injury report.
Cavaliers at Thunder picks and predictions
Prediction
Thunder 118, Cavaliers 111
Moneyline
The Thunder (-140) aren't worth playing, even at a reasonable price. When playing a favorite of -3 or fewer points, there is no sense paying up rather than laying the little bit of points.
PASS, and play the spread instead.
Against the spread
The THUNDER -2.5 (-105) are a much better play laying the little bit of points, rather than playing straight up. SGA was on fire in the front end of the home-and-home. And, OKC has dominated this series, winning and covering 4 straight meetings since Jan. 16, 2025, while going 7-1 SU/ATS in the past 8 installments since 2023.
Over/Under
BET OVER 227.5 (-115) is the lean, but go with a half-unit play at most.
While the Under cashed by a half-point at most shops Monday, the Over is 5-1 in the past 6 meetings in this series. The Thunder has allowed 112+ points in 4 consecutive outings, while Cavaliers have allowed 111+ in each of its 7 games to date.
Best prop bet
Bet Cavaliers G DONOVAN MITCHELL OVER 33.5 POINTS + REBOUNDS + ASSISTS (-120).
Playing PRA combos are fun, especially when you use a star player. You know you're going to get production, and plentiful shots to keep trying, in the event of a slow start or off night.
Spida is averaging 21.9 points, 5.4 assists and 5.3 rebounds per game, so he simply needs to hit his average to cash. In Monday's game, he had 17 points on a dismal 6 of 17 shooting, with 11 assists and 5 rebounds.
Betting odds calculator
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This article originally appeared on USA TODAY: Cleveland Cavaliers at Oklahoma City Thunder odds, picks and predictions
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