The Oklahoma State Cowboys (5-2, 3-1 Big 12) visit the Iowa State Cyclones (3-4, 1-3) Saturday night for a 7 p.m. ET (FOX) kickoff from Jack Trice Stadium in Ames, Iowa. Let's analyze college football odds around the Oklahoma State vs. Iowa State odds and make our expert college football picks and predictions for the best bets.
Oklahoma State got back in the win column in a big way last week with a 57-24 victory over Colorado, covering as a 12.5-point home favorite with the Over (55.5) hitting. QB Drew Mestemaker threw for 386 yards and 4 touchdowns while RB Caleb Hawkins rushed for 120 yards. WR Justin Bowick made the most of his 5 receptions, going for 138 yards and a TD in the blowout.
Iowa State has dropped back-to-back games after being demolished
39-3 against Arizona last week, failing to cover as an 11.5-point road underdog with the Under (51.5) hitting. QBs Jaylen Raynor and Connor Moberly went a combined 15-for-27 with 169 yards, while the Cyclones were held to just 52 rushing yards in the losing effort.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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Oklahoma State at Iowa State odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 9:20 p.m. ET.
- Moneyline (ML): Oklahoma State -350 (bet $350 to win $100) | Iowa State +280 (bet $100 to win $280)
- Against the spread (ATS): Oklahoma State -9.5 (-110) | Iowa State +9.5 (-108)
- Over/Under (O/U): 57.5 (O: -112 | U: -105)
Oklahoma State at Iowa State picks and predictions
Prediction
Oklahoma State 48, Iowa State 27
Moneyline
PASS.
There is minimal value on the Cowboys (-350) to come out victorious on Saturday night.
Against the spread
BET OKLAHOMA STATE -10 (-110).
The Cowboys have been dominant against the spread this season, covering in each of their last 6 games for a 6-1 ATS record. They have covered in each of their last 3 as favorites, all of which they won by at least 14 points.
The Cyclones are just 3-4 ATS this season and have failed to cover in each of their last 3 games as underdogs, including back-to-back games in which they entered as 11.5-point underdogs. They have managed to score just 13 points combined over their previous 2 games, which does not bode well for them keeping pace against a fast-paced Cowboys team.
Over/Under
BET OVER 57.5 (-110).
While the Cyclones have not performed well offensively of late, even a few scores from the home team will aid the total.
The Cowboys' offense is the primary reason to take the Over. They have scored 41 or more points in 4 of their last 5, including 57 or more twice in that span. They have a 5-2 Over record this season. Their defense has underperformed, allowing at least 24 in each of their last 4 and in 6 of their 7 games this season.
Best prop bet
BET ANY TEAM TO SCORE 40+ POINTS: YES (+145 on DraftKings Sportsbook).
The Cowboys have topped 40 in 4 of their last 5 games, scoring at least 39 in 5 of their last 6. Their offense has been firing on all cylinders, both through the air and on the ground. The Cyclones are fresh off a 39-point outing from their opponents and have allowed at least 31 in 3 of their last 4. In a game that has all the making of a high-scoring affair, this is an intriguing bet.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Oklahoma State Cowboys at Iowa State Cyclones odds, picks and predictions
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