The No. 18 Iowa Hawkeyes (4-1, 1-1 Big Ten) and Washington Huskies (3-2, 0-2) meet Friday for a Week 6 Big Ten clash. Kickoff from Husky Stadium in Seattle, Washington, is set for 9 p.m. ET. Let's analyze college football odds around the Iowa vs. Washington odds and make our expert college football picks and predictions for the best bets.
Iowa lost to the No. 6 Ohio State Buckeyes 31-14 Saturday, failing to cover as a 14.5-point home favorite with the Under (46.5) cashing. The Hawkeyes were riding a 4-game win streak to start the season, including a last-second TD on the road to beat the Michigan Wolverines in Week 4. Iowa has gone 3-2 against the spread (ATS) and 1-4 Over/Under. It has been led by a rock-solid defense, which has blanked its
opponents twice this season, and is allowing just 12.6 points per game, eighth-best in the nation.
Washington was undefeated going into conference play, but has dropped 2 straight contests by a combined 7 points. It lost 25-21 to the No. 17 USC Trojans Saturday, covering as a 7.5-point road underdog as the Under (58.5) hit. Washington is 1-4 ATS and 2-3 O/U. It is led by dual-threat QB Demond Williams Jr., who has 1,327 passing yards and 8 TDs and has rushed for 191 yards and 2 scores.
Iowa has won 2 straight (last one 40–16 in Iowa City in 2024) and leads the all-time series 4-3.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
Watch NCAA football on Fubo!
Iowa at Washington odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 1:07 p.m. ET.
- Moneyline (ML): Iowa +130 (bet $100 to win $130) | Washington -160 (bet $160 to win $100)
- Against the spread (ATS): Iowa +3 (-105) | Washington -3 (-115)
- Over/Under (O/U): 41.5 (O: -110 | U: -110)
Iowa at Washington picks and predictions
Prediction
Washington 21, Iowa 20
Moneyline
PASS.
Avoid this play. Iowa (+130) could be worth a look, but it is better played on the spread than to pull off the upset.
Against the spread
BET IOWA +3 (-105).
The Hawkeyes' defense has been dominant this season. They've only allowed more than 20 points once, and that was to an Ohio State team with the country's best receiver. Iowa ranks 41st of 138 programs in opponents' yards per play (4.9) and should be able to limit a one-dimensional Washington offense. It is 1-0 ATS as a single-digit underdog.
The Huskies have had major struggles in conference play, and while they covered against USC, they lost 27-24 to the Minnesota Golden Gophers as a double-digit favorite. Washington has scored 24 points or fewer in 4 of 5 games, despite being a favorite of more than 23 points in 3 of those contests. It hasn't proven that it can hang with quality programs. While Iowa's offense isn't the most dynamic, it has kept games close, even on the road.
Over/Under
BET UNDER 41.5 (-110).
Neither side has shown they have a capable and consistent offense.
The Huskies rank 130th in third-down conversion rate (23.53%) and can't sustain drives, partially due to a lacking run game. They are 2-3 O/U and 0-1 O/U in games with a single-digit spread. The Hawkeyes are 0-2 O/U in conference play and 0-2 O/U with a total of 43 points or fewer.
Betting odds calculator
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow SportsbookWire on X at SportsBookWire and on Facebook.
College sports coverage from USA TODAY Sports Media Group:
Alabama / Auburn / BYU / Clemson / Colorado / Duke / Florida / Florida State / Georgia / Iowa / Kentucky / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Tennessee / Texas / Texas A&M / Texas Tech / UCLA / USC / Washington / Wisconsin / College Sports Wire / High Schools
This article originally appeared on Sportsbook Wire: Iowa Hawkeyes at Washington Huskies odds, picks and predictions
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.













