The Virginia Tech Hokies (5-2, 2-2 ACC) and Clemson Tigers (4-2, 2-1) meet Saturday in a Week 8 ACC clash. Kickoff from Memorial Stadium in Clemson, South Carolina, is set for 7 p.m. ET (ESPN). Let's analyze college football odds around the Virginia Tech vs. Clemson odds and make our expert college football picks and predictions for the best bets.
The Hokies edged the Georgia Tech Yellow Jackets 34-24 last Saturday, covering as 8.5-point home favorites with the Over (55.5) hitting. Virginia Tech snapped a 2-game losing streak with the win, having rattled off 4 straight victories prior to that. The Hokies are led by QB Ethan Grunkemeyer, who has 20 touchdowns (15 passing, 1 rushing) and an ACC-leading 1,984 passing yards, which is fifth-best in the country.
Clemson is coming off a Week 7 cupcake victory against the Charleston Southern Buccaneers, winning 37-0 yet failing to cover as a massive 42.5-point home favorite as the Under (57.5) cashed. Before throttling the Buccaneers, the Tigers suffered their second loss of the season in a 41-13 home defeat against the then-No. 4, now-No. 1 Miami Hurricanes. Clemson is 4-0 against unranked opponents and 0-2 against ranked teams (losses to Miami and then-No. 13, now-No. 17 LSU). The Tigers are 2-4 against the spread (ATS) on the season.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
Watch NCAA football on Fubo!
Virginia Tech at Clemson odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10 a.m. ET.
- Moneyline (ML): Virginia Tech +120 (bet $100 to win $120) | Clemson -145 (bet $145 to win $100)
- Against the spread: Virginia Tech +3 (-120) | Clemson -3 (-108)
- Over/Under (O/U): 48.5 (O: -110 | U: -108)
Virginia Tech at Clemson picks and predictions
Prediction
Clemson 31, Virginia Tech 20
Moneyline
PASS.
Clemson (-145) is the preferred play, but it is just slightly too expensive to consider here. AVOID and look below for the better value.
Against the spread
BET CLEMSON -3 (-108).
The Hokies' offense lives or dies by Grunkemeyer's success, ranking 47th of 138 programs in passing play percentage. He has completed 72.9% of his pass attempts this season but will be facing a stout Clemson defense. The Tigers sit 18th (56.73%) in opponents' completion percentage this season. They should be able to make life difficult for Va. Tech, especially in front of a rocking crowd.
Clemson's sweet spot this season has been as a single-digit favorite. It is 0-2 ATS as an underdog and 0-2 ATS as a double-digit favorite, but it is 2-0 ATS as a single-digit favorite. The Tigers have yet to allow more than 20 points in a game against an unranked side. That streak shouldn't be snapped Saturday.
Over/Under
BET OVER 48.5 (-110).
Clemson has been consistently inconsistent on the total this season, trading off going Over and Under in each contest and is coming off an Under performance against Charleston Southern. The Tigers have scored at least 28 points in 2 of their last 3 home games.
The Hokies are 5-2 O/U this season as the offense has produced well. They've scored at least 20 points in every game and have tallied at least 33 points in each of their contests with a single-digit spread (3-0).
Betting odds calculator
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow SportsbookWire on X at SportsBookWire and on Facebook.
College sports coverage from USA TODAY Sports Media Group:
Alabama / Auburn / BYU / Clemson / Colorado / Duke / Florida / Florida State / Georgia / Iowa / Kentucky / LSU / Michigan / Michigan State / Nebraska / North Carolina / Notre Dame / Ohio State / Oklahoma / Oregon / Penn State / Tennessee / Texas / Texas A&M / Texas Tech / UCLA / USC / Washington / Wisconsin / College Sports Wire / High Schools
This article originally appeared on Sportsbook Wire: Virginia Tech Hokies at Clemson Tigers odds, picks and predictions
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.













