The Buffalo Bulls (5-3, 3-1 MAC) and the Miami (Ohio) RedHawks (5-3, 3-1) meet Tuesday at Yager Stadium in Oxford, Ohio. Kickoff is scheduled for 8 p.m. ET (ESPN). Let's analyze college football odds around the Buffalo vs. Miami (Ohio) odds and make our expert college football picks and predictions for the best bets.
Miami (Ohio) leads all-time series 18-9. The RedHawks have won the past 2 meetings, including last season's 37-20 victory in Buffalo on Nov. 19, 2025. In the most recent battle in Oxford, Miami won 23-10 in 2023.
The winner of this game will be bowl eligible, while remaining in the hunt for the MAC Championship Game. While a second conference loss won't necessarily eliminate Buffalo or Miami, it will be a huge obstacle.
Buffalo has
won 3 in a row, while covering 4 consecutive outings. That includes a 31-24 win over Bowling Green Falcons last time out Oct. 24 as a 2.5-point favorite as the Over (44.5) cashed. That halted a 3-game Under run.
Miami eased by Central Michigan Chippewas 28-27, but it failed as a 3.5-point favorite as the Over (41.5) easily cashed. The RedHawks have won 3 in a row, but Miami is just 1-3 against the spread (ATS) in the past 4 games, while the Over is 3-1 in the same 4-game span.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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Buffalo at Miami (Ohio) odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:42 a.m. ET.
- Moneyline (ML): Buffalo +195 (bet $100 to win $195) | Miami (Ohio) -240 (bet $240 to win $100)
- Against the spread: Buffalo +6.5 (-105) | Miami (Ohio) -6.5 (-115)
- Over/Under (O/U): 44.5 (O: -110 | U: -110)
Buffalo at Miami (Ohio) picks and predictions
Prediction
Miami (Ohio) 23, Buffalo 20
Moneyline
Miami (Ohio) (-235) will set you back nearly 2 1/2 times your potential return, and that's way too much risk for not nearly enough reward. You can't bet it straight up, although as part of a multi-leg parlay of 3 or more legs, it might be OK.
PASS.
Against the spread
BUFFALO +6.5 (-105) is an OK play, although for math purposes, taking BUFFALO +7.5 (-145) - ALTERNATE SPREAD makes me feel a little bit better. I don't think this game is going to be a blowout, but I could see this game have a 7-point difference. That's why buying up and taking an extra point makes sense.
The Bulls are on a 4-game cover streak, including 2-0 ATS as an underdog. In fact, Buffalo won 23-8 at Toledo as an 18.5-point underdog in its most recent road trip.
Over/Under
UNDER 44.5 (-110) is the lean, but be careful. While the Under is 3-1 in the past 4 games for the Bulls, the Over has cashed in 3 of the past 4 outings for the RedHawks.
The Under has cashed in 2 of the past 3 meetings in this series, with the winning team averaging 28.0 points per game, with the losing side managing just 16.7 PPG in the past 6 in the series.
Betting odds calculator
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow Daniel Dobish on X at @danieledobish. Follow SportsbookWire on X at SportsBookWire and on Facebook.
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This article originally appeared on Sportsbook Wire: Buffalo Bulls at Miami (Ohio) RedHawks odds, picks and predictions
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