The Colorado Rockies (55-88) and New York Yankees (81-62) open a 3-game series Tuesday in New York, New York. First pitch from Yankee Stadium is at 7:05 p.m. ET. Let's analyze MLB odds around the Rockies vs. Yankees odds and make our expert MLB picks and predictions for the best bets.
2025 season series: Yankees won 2-1
The Rockies are 5-14 in their last 19 games. They were idle Monday after losing 2 out of 3 games at home to the St. Louis Cardinals. They lost the finale Sunday 10-8 as +113 underdogs with the Over (11) cashing. They had a 5-0 lead and allowed the Cardinals to score 6 times in the fifth inning. LF Jake McCarthy went 3 for 5 with 2 runs and 3 RBIs, including a home run.
The Yankees were also idle Monday. They are 4 games out of first
place in the AL East, but are the No. 1 Wild Card. They went 3-3 on their road trip and lost 2 of 3 to the San Diego Padres, losing the finale 4-3 Sunday as +102 underdogs with a push for the total (7). They fell behind 4-0, scoring zero runs off Padres SP Michael King, but their rally against their bullpen fell short.
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Rockies at Yankees projected starters
RHP Gabriel Hughes vs. RHP Cam Schlittler
Hughes (0-6, 6.19 ERA) makes his 11th career start and 12th appearance. The 25-year-old rookie has a 1.43 WHIP, 3.6 BB/9 and 7.2 K/9 in 52 1/3 innings.
- Last start: No-decision, 4 2/3 IP, 1 ER, 4 H, 2 BB, 4 K in 4-2 home win over Baltimore Orioles last Tuesday
- Making first appearance vs. Yankees
- 2026 road splits: 0-3, 9.00 ERA (24 IP, 24 ER), 1.71 WHIP, 6.4 K/9 in 5 starts
Schlittler (12-6, 2.04 ERA) makes his 30th start. He has a 0.94 WHIP, 2.2 BB/9 and 11.0 K/9 in 171 2/3 innings.
- Last start: No-decision, 8 IP, 1 ER, 2 H, 0 BB, 9 K in 6-3 10-inning win at Los Angeles Angels Wednesday
- Facing Rockies for first time
- 2026 home splits: 4-4, 3.41 ERA (68 2/3 IP, 26 ER), 1.25 WHIP, 11.4 K/9 in 13 starts
Rockies at Yankees odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:01 a.m. ET.
- Moneyline (ML): Rockies +275 (bet $100 to win $275) | Yankees -350 (bet $350 to win $100)
- Run line (RL)/Against the spread (ATS): Rockies +2.5 (-135) | Yankees -2.5 (+110)
- Over/Under (O/U): 8 (O: -110 | U: -110)
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Rockies at Yankees picks and predictions
Prediction
Yankees 6, Rockies 3
Moneyline
This is not a good matchup for the Rockies. They are the worst team in the National League with the second-worst road record in baseball. They have a rookie who has struggled facing the second-best team in the American League with a starter leading the league in ERA.
The Rockies are 20-51 against teams with at least a .500 record. The Yankees have won Schlittler's last 3 outings.
Expect the Yankees to win, but -350 odds are never a good value to bet.
PASS.
Run line/Against the spread
With a 2.5-run spread, things are trickier. The Rockies' last 6 losses have been by 2 or fewer runs. They are 39-30 ATS on the road and have the same mark as home underdogs.
Seven of the Yankees' last 8 wins have been by at least 3 runs, though. They are 26-32 ATS as home favorites, though.
Four of the Rockies' 8 losses in Hughes' starts have been by 3 or more runs.
BET YANKEES -2.5 (+110).
Over/Under
Six of the Yankees' last 8 games have had totals above 8. In 7 of Hughes' 11 appearances, the total has been at least 8.
Nine of the Rockies' last 14 games have had totals of 8 or higher.
BET OVER 8 (-110).
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Colorado Rockies at New York Yankees odds, picks and predictions
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