The Arizona State Sun Devils (4-3, 2-2) and No. 9 BYU Cougars (6-1, 3-1) meet Saturday for a Week 9 Big 12 showdown. Kickoff from LaVell Edwards Stadium in Provo, Utah, is set for 3:30 p.m. ET (FOX). Let's analyze college football odds around the Arizona State vs. BYU odds and make our expert college football picks and predictions for the best bets.
Arizona State beat the Kansas State Wildcats 28-17 Saturday, covering as a 1.5-point home underdog with the Under (51.5) cashing. In the week prior, it had its most high-profile game, but came up well short in a 53-25 road loss to the No. 14 Texas Tech Red Raiders. The Sun Devils, who changed quarterbacks in the middle of the season, are now starting Mikey Keene, a Michigan Wolverines transfer. They
have traded off winning and losing in each game this season and are 3-4 against the spread (ATS).
BYU has seen its greatest highs and lowest lows in the last two weeks. The Cougars came up short for the first time this season, losing to the UCF Knights 39-31 and failing to cover as a 7.5-point road favorite Saturday. The Over (43.5) hit. Prior to that, BYU beat the No. 6 Notre Dame Fighting Irish 28-24. The Cougars are 6-1 ATS on the season and have been led by their defense, having allowed more than 24 points just once in 2026.
Arizona State won 28-24 in the last meeting in 2024 and leads the all-time series 21-8-1
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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Arizona State at BYU odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 10:32 a.m. ET.
- Moneyline (ML): Arizona State +550 (bet $100 to win $550) | BYU -750 (bet $750 to win $100)
- Against the spread (ATS): Arizona State +16.5 (-110) | BYU -16.5 (-108)
- Over/Under (O/U): 48.5 (O: -105 | U: -112)
Arizona State at BYU picks and predictions
Prediction
BYU 34, Arizona State 14
Moneyline
PASS.
Avoid this play. BYU (-750) should win with ease, but it is too expensive to consider here.
Against the spread
BET BYU -16.5 (-108).
The Cougars have been a covering machine this season. They are 4-0 ATS at home and have allowed 17 points or fewer in the 3 home games in which they were favored to win. BYU should also be ready to prove itself, coming off an embarrassing road loss.
The Sun Devils defense has been atrocious against quality sides. They faced the Texas A&M Aggies earlier this season and allowed 48 points. On top of that, they allowed 53 points to Texas Tech and 55 points to the Baylor Bears. While Keene has been better for this offense, the defense has been terrible. Arizona State is 0-2 ATS as a double-digit underdog as well.
Over/Under
BET OVER 48.5 (-105).
The Sun Devils, as noted above, haven't been able to get stops against quality foes this season. They are 2-0 O/U as a double-digit underdog and 2-0 O/U in true road games.
For BYU, while it should dominate, it has had its 2 worst defensive showings of the season in the last 2 weeks, allowing 31.5 points per game across its last 2 contests. The Cougars have gone Over in both of those and are 4-3 O/U on the year.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Arizona State Sun Devils at BYU Cougars odds, picks and predictions
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