The FIU Panthers (3-2, 1-0 CUSA) and the Jacksonville State Gamecocks (4-2, 2-0) meet Tuesday in Conference USA action at AmFirst Stadium in Jacksonville, Alabama. Kickoff is scheduled for 8 p.m. ET (ESPNU). Let's analyze college football odds around the FIU vs. Jacksonville State odds and make our expert college football picks and predictions for the best bets.
FIU cruised to a 22-3 home victory over the New Mexico State Aggies last Wednesday, covering as a 6.5-point favorite while the Under (46.5) cashed. RB Devonte Lyons led the ground attack with 78 rushing yards, while RB Anthony Carrie added 37 yards and a TD. PK Robert Czeremcha was 5 for 5 on field goals, including a 52-yarder.
Jacksonville State made it 3 straight wins with a thrilling
27-26 victory over the Kennesaw State Owls last Wednesday in a rematch of the 2025 Conference USA title game. K Garrison Rippa drilled the go-ahead field goal in the final minute before S Rob Billings IV sealed the win with an interception seconds later. QB Caden Creel threw for 311 yards with 1 TD and 1 INT, with WR Deondre Johnson accounting for 112 receiving yards on just 4 catches.
Jacksonville State has won 3 of the 4 meetings, but the Panthers got the last laugh, snapping a 3-game losing streak against the Gamecocks with a 27-21 home victory last season. FIU covered as a 2.5-point favorite in that matchup, while the Under (56.5) cashed.
– Rankings: US LBM Coaches Poll, conducted by the American Football Coaches Association and USA TODAY Sports
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FIU at Jacksonville State odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:15 p.m. ET.
- Moneyline (ML): Southern Miss +120 (bet $100 to win $120) | Troy -145 (bet $145 to win $100)
- Against the spread (ATS): Southern Miss +3 (-112) | Troy -3 (-108)
- Over/Under (O/U): 43.5 (O: -108 | U: -110)
FIU at Jacksonville State picks and predictions
Prediction
Jacksonville State 21, FIU 17
Moneyline
PASS.
I've got the Gamecocks (-145) winning this game, but I don't love paying all that juice, I'll take my bet to the spread.
Against the spread
BET JACKSONVILLE STATE -3 (-108).
Jacksonville State is riding a 3-game winning streak and has been tough to beat at home. Since joining the FBS in 2023, the Gamecocks have lost just 3 home games, giving them an advantage in this CUSA showdown.
Creel has been a major part of that success, throwing 10 TD passes and adding 405 rushing yards and 4 scores. He threw for 311 yards last week against Kennesaw State.
FIU has won 2 straight and hasn't allowed more than 20 points in a game this season, but Kohl has struggled with turnovers. His 7 interceptions in 5 games lead Conference USA.
The Panthers' defense presents a challenge, but Jacksonville State's quarterback advantage, strong home-field record and recent momentum should make the difference.
Over/Under
BET UNDER 43.5 (-110).
Jacksonville State has been involved in plenty of high-scoring games, with 4 of its 6 contests finishing above the total. The Gamecocks have scored 18 offensive TDs. FIU has allowed just 6 points over its last 2 games, but Jacksonville State's explosive passing attack presents a much tougher challenge.
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This article originally appeared on Sportsbook Wire: FIU Panthers at Jacksonville State Gamecocks odds, picks and predictions
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