The Cleveland Browns (5-3) and the New Orleans Saints (2-5) meet Sunday for a Week 9 game at Caesars Superdome in New Orleans, Louisiana. Kickoff is scheduled for 1 p.m. ET (CBS). Let's analyze NFL odds around the Browns vs. Saints odds and make our expert NFL picks and predictions for the best bets.
Browns lead all-time series 13-7; Saints have won the past 3 meetings, including a 35-14 rout in New Orleans Nov. 17, 2024, in the most recent meeting. Cleveland's last victory in the series came on Sept. 14, 2014, a 26-24 victory at home. Its last win in New Orleans came on Oct. 24, 2010, a 30-17 victory.
Cleveland is looking to rebound from a 27-6 beating in Pittsburgh last weekend, as the Browns slipped out of first place in the AFC North Division.
It was the most lopsided loss since a 34-10 setback in Jacksonville back in Week 1. Still, Cleveland is 5-2 against the spread (ATS) in the past 7 games, while the Under has cashed in 3 of the Browns' past 4 outings.
Browns QB Deshaun Watson took helmet-to-helmet contact in Pittsburgh last week. He left briefly, with QB Shedeur Sanders coming in for 2 completions on 2 attempts. Watson was cleared on Monday but experienced post-concussion symptoms Tuesday and has been in the protocol since. If he cannot go, Sanders would start.
New Orleans had a bye in Week 8 after a trip to Paris to meet the aforementioned Steelers. The Saints lost 16-10 as 2.5-point underdogs as the Under (43.5) cashed. New Orleans has dropped 4 of the past 5 games, while also going 1-4 ATS in the span. It is winless with an 0-3 ATS mark in 3 games at the Caesars Superdome this season, too.
The Saints tried to trade RB Kendre Miller but presumably could not find a partner. As such, the team waived him. So, RB Alvin Kamara figures to start, while RB Audric Estime, who played a game with the Browns against Baltimore and scored a touchdown, gets a shot as the primary backup.
Browns at Saints odds
Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 6 p.m. ET.
- Moneyline (ML): Browns +140 (bet $100 to win $140) | Saints -175 (bet $175 to win $100)
- Against the spread (ATS): Browns +3 (-102) | Saints -3 (-118)
- Over/Under (O/U): 42.5 (O: -108 | U: -110)
Browns at Saints injuries
Browns
- DT Maliek Collins (elbow) out
- QB Deshaun Watson (concussion) questionable
Saints
- OT Kelvin Banks Jr. (ankle) questionable
- RB CJ Donaldson (shoulder, concussion) out
- CB Martin Emerson (shin) questionable
- OT Asim Richards (thumb) questionable
- WR Jordyn Tyson (hamstring) questionable
USA TODAY Sports Fantasy: Sync your ESPN, Yahoo, CBS or Sleeper league in seconds to unlock custom roster advice, expert projections, and start/sit recommendations built for your team. Stop guessing and start winning. Sync your league now!
Watch the NFL on Fubo!
Browns at Saints picks and predictions
Prediction
Saints 22, Browns 16
Moneyline
The Saints (-175) will cost you too much for a little bit of insurance. New Orleans is coming off a bye and has had 2 full weeks to get ready for the game. The Saints might also catch a break with the backup Sanders behind center. If Watson is inactive, go a little heavier on the Saints laying the points.
PASS.
MONDAY NIGHT FOOTBALL: Best prop bets
Against the spread
The SAINTS -3 (-118) are well-rested and ready to go after a bye. The Browns are in pretty good shape, too, but the injury to Watson is a concern.
Cleveland has lost 2 road games by 21 or more points this season, and it has performed much worse away from home than in front of the fans at Huntington Bank Field.
Over/Under
UNDER 42.5 (-110) is the lean, but go with a half-unit play at most.
The Cleveland offense could be a little disjointed if Watson isn't in there, and it might be more of a ground-based attack, which favors the Under.
Best prop bet
SAINTS RB AUDRIC ESTIME OVER 26.5 RUSHING YARDS (-113).
Estime could be a real wild card. He was cut loose by the Browns when RB Dylan Sampson was activated from the reserve/injured list. He could be running with a little extra incentive.
Betting odds calculator
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow Daniel Dobish on X at @danieledobish. Follow SportsbookWire on X at SportsBookWire and on Facebook.
Access more NFL coverage:
USA TODAY Sports Fantasy | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire | High schools
This article originally appeared on Sportsbook Wire: Cleveland Browns at New Orleans Saints odds, picks and predictions
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.
