The New York Giants (3-1) and Washington Commanders (1-3) meet Sunday in Landover, Maryland, for a NFC East Week 5 battle. Kickoff from Northwest Stadium is at 1 p.m. ET (FOX). Let's analyze NFL odds around the Giants vs. Commanders odds and make our expert NFL picks and predictions for the best bets.
The Giants improved to 3-1 in Week 4 with a 36-24 home victory over the Arizona Cardinals. New York pulled off the upset as a 2.5-point underdog, while the Over (44.5) cashed. QB Jameis Winston threw for 250 yards, 3 touchdowns and 2 interceptions. WR Malik Nabers hauled in 6 catches for 112 yards and a touchdown in the win.
The Commanders' rough start continued in Week 4 with a 30-13 loss to the Indianapolis Colts in London. Washington failed to cover
as a 5.5-point underdog, while the Under (46.5) cashed. Injuries made matters worse, as QB Marcus Mariota, starting for the injured QB Jayden Daniels (elbow), exited after Washington's second drive with a knee injury. Third-string rookie QB Athan Kaliakmanis took over, throwing for 186 yards, 1 touchdown and 1 interception in the loss. Daniels is expected back in this one.
Washington has had the Giants' number lately, winning and covering 4 straight meetings. The Commanders took the most recent matchup 29-21 Dec. 14, with the Over (45.5) cashing.
Watch the NFL on Fubo!
Giants at Commanders odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 11:10 a.m. ET.
- Moneyline (ML): Giants +155 (bet $100 to win $155) | Commanders -190 (bet $190 to win $100)
- Against the spread (ATS): Giants +3.5 (-108) | Commanders -3.5 (-110)
- Over/Under (O/U): 41.5 (O: -110 | U: -108)
Giants at Commanders injuries
Giants
- QB Jaxson Dart (knee) out for season
- DE Chauncey Golston (neck) out
- S Jason Pinnock (concussion) out
Commanders
- CB Trey Amos (ankle) questionable
- S Percy Butler (hamstring) out
- S Nick Cross (illness) out
- WR Stefon Diggs (hamstring) out
- QB Marcus Mariota (knee) out
- WR Terry McLaurin (hamstring) questionable
- RB Jeremy McNichols (quad) questionable
- DE Charles Omenihu (Groin, Ankle) out
- S Tyler Owens (hamstring) out
- DE Deatrich Wise (quad) questionable
USA TODAY Sports Fantasy: Sync your ESPN, Yahoo, CBS or Sleeper league in seconds to unlock custom roster advice, expert projections, and start/sit recommendations built for your team. Stop guessing and start winning. Sync your league now!
Giants at Commanders picks and predictions
Prediction
Giants 27, Commanders 20
Moneyline
BET GIANTS (+155).
The Giants enter Week 5 with momentum after improving to 3-1, while Washington continues to battle injuries during a disappointing 1-3 start. New York has already won twice as an underdog this season and faces a Commanders team coming off a 30-13 loss to Indianapolis.
While Daniels is expected to return, his injured non-throwing arm could limit his mobility, which is one of the biggest strengths of his game. The Giants' aggressive pass rush should make things even tougher for Washington's quarterback.
Winston is coming off his best game against Arizona and faces a Washington secondary that has struggled against the pass. Nabers dominated last week, catching 6 passes for 112 yards and a touchdown.
Washington has dominated this rivalry recently, but its growing injury list and defensive struggles give New York a real opportunity Sunday.
Against the spread
PASS.
Taking the Giants with the points offers a little extra protection, but the spread isn't particularly appealing here. New York has a legitimate chance to win outright, making the moneyline the better option to me.
Over/Under
BET OVER 41.5 (-110).
Daniels' return should give Washington's offense a boost, while Winston faces a Commanders secondary that has struggled against the pass. Every Washington game this season has finished with more than 42.5 points, and opponents of these 2 teams have combined to average 50.3 points per game. Two of their last 3 meetings have also been high-scoring, including Washington's 29-21 victory last December.
Best prop bet
GIANTS WR MALIK NABORS OVER 57.5 RECEIVING YARDS (-115).
Nabers is coming off his best performance of the season, catching 6 passes for 112 yards and a touchdown against Arizona. He accounts for 23.6% of the Giants' targets and 29.1% of their air yards, making him a key weapon for Winston. Washington ranks 25th in passing yards allowed, surrendering 242.5 per game, and has struggled against wide receivers. Nabers also caught 5 passes for 71 yards in his previous meeting with the Commanders.
Betting odds calculator
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow SportsbookWire on X at SportsBookWire and on Facebook.
Access more NFL coverage:
USA TODAY Sports Fantasy | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire | High schools
This article originally appeared on Sportsbook Wire: New York Giants at Washington Commanders odds, picks and predictions
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.
