The Boston Celtics (8-2) visit the Philadelphia 76ers (9-2) Tuesday for a 8 p.m. ET tip-off at Xfinity Mobile Arena in Philadelphia, Pennsylvania. Let's analyze NBA odds around the Celtics vs. 76ers odds and make our expert NBA picks and predictions for the best bets.
2025-26 season series: Celtics won 3-1 with a split in Philadelphia
The Celtics and 76ers clash in the biggest game of the year so far in the Eastern Conference. This matchup features the No. 2 seed visiting the first place team's home court. Not to mention the offseason storyline, which features these 2 sides facing off following their blockbuster trade which sent G Jaylen Brown to Philadelphia with F Paul George heading in the opposite direction.
Boston heads to Philadelphia on a 3-game
winning streak. George (20.4 point, 5.2 rebounds per game) paced his team with a team-high 27 points in their last outing, a 117-97 win against the Milwaukee Bucks. F Jayson Tatum (27.1 PPG, 7.8 assist per game) added 21 points and 6 assists while C Neemias Queta (9.5 PPG, 6.2 RPG) had 13 points and 9 rebounds.
The 76ers' new experiment this season highlighted by the addition of Brown and F LeBron James got back to winning ways on Sunday against the Chicago Bulls in a 127-121 win. Their big names led the way. Brown (22.3 PPG, 6.7 RPG) had a team-high 29 points with 7 rebounds, meanwhile, G Tyrese Maxey (26.9 PPG, 5.5 APG) had 27 points and 7 assists. James (15.6 PPG, 6.7 APG) put away 22 points, meaning the trio combined for 78 points against the Bulls.
Both Boston (3-7) and Philadelphia (3-8) have hit the Over just 3 times this year. The Celtics are .500 (5-5) against the spread (ATS) while the 76ers are 6-5 ATS.
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Celtics at 76ers odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:01 p.m. ET.
- Moneyline (ML): Celtics -120 (bet $120 to win $100) | 76ers +100 (bet $100 to win $100)
- Against the spread (ATS): Celtics -1.5 (-110) | 76ers +1.5 (-110)
- Over/Under (O/U): 217.5 (O: -110 | U: -110)
Celtics at 76ers key injuries
Celtics
Not submitted yet; had none for Sunday game
76ers
- F Dominick Barlow (back) out
- C Adem Bona (back).out
For most recent updates: Official NBA injury report.
Celtics at 76ers picks and predictions
Prediction
76ers 112, Celtics 110
Moneyline
BET 76ERS (+100).
Both teams have been hot this season as we head into this battle for first place in the Eastern Conference. The home underdog is too tempting to pass up here. Boston is riding a 3-game winning streak, but the Sixers having their top guns break out last game and a chance to defend their home court is a good combo to ride with. And to this point, we haven't even mentioned C Joel Embiid. Philadelphia still has him, too. That's a lot of firepower and challenges for the Celtics to overcome.
Against the spread
PASS.
If you feel like riding with 1 extra point in your pocket on the 76ERS +1.5 (-110), have at it.
Over/Under
BET OVER 217.5 (-110).
Both teams have had the Under in the sights for most of the season and for good reason. The Celtics and 76ers both have top-6 defenses in the NBA right now. But both teams have had their top shooter hot as of late, making a lowest point total on the entire NBA's Tuesday slate a number to take advantage of.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Boston Celtics at Philadelphia 76ers odds, picks and predictions
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