The Washington Commanders (0-1) and Dallas Cowboys (0-1) clash Sunday in an NFC East game in Week 2. Kickoff from AT&T Stadium in Arlington, Texas, is at 4:25 p.m. ET (FOX). Let's analyze NFL odds around the Commanders vs. Cowboys odds and make our expert NFL picks and predictions for the best bets.
The Commanders lost their season opener 24-22 at the Philadelphia Eagles, covering the 5.5-point spread as underdogs with the Over (43.5) cashing. QB Jayden Daniels threw 2 TD passes, but Eagles QB Jalen Hurts threw 3.
The Cowboys lost 29-20 Sunday to the New York Giants as 3.5-point road favorites with the Over (47.5) cashing. They never led in the game. Giants QB Jaxson Dart had 3 TD passes against what was supposed to be a revamped Dallas defense.
Cowboys QB Dak Prescott threw 2 TDs and had 1 INT.
The Cowboys lead the all-time series 81-49-2 and are 8-2 against the Commanders in their last 10 meetings, including a sweep in 2025. The Cowboys beat the Commanders 30-23 at Washington as 9.5-point favorites after winning the first meeting 44-22 in Dallas.
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Commanders at Cowboys odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:06 a.m. ET.
- Moneyline (ML): Commanders +175 (bet $100 to win $175) | Cowboys -210 (bet $210 to win $100)
- Against the spread (ATS): Commanders +4 (-108) | Cowboys -4 (-110)
- Over/Under (O/U): 51 (O: -110 | U: -110)
Commanders at Cowboys key injuries
Commanders
- DT Javon Kinlaw (back) questionable
- LB Frankie Luvu (groin) out
- TE Chig Okonkwo (hamstring) out
Cowboys
- S Malik Hooker (forearm) out
- LB DeMarivion Overshown (hamstring) out
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Commanders at Cowboys picks and predictions
Prediction
Cowboys 31, Commanders 24
Moneyline
The Cowboys are expected to compete in the NFC East. Both teams are desperate to win, as the loser will be 0-2 in the division. The Cowboys have dominated the all-time series and have won 4 of the last 5 meetings in Arlington.
The Cowboys have the better offensive weapons, and they are expected to be better defensively. This is their home opener, which always means a little extra juice in the matchup.
Dallas should win, but the spread gives you better value.
PASS.
Against the spread
The last 14 Dallas wins over Washington have been by more than 4 points. The Cowboys are 7-1 ATS in their last 8 wins over the Commanders.
BET COWBOYS -4 (-108).
Over/Under
The Over is 5-1 in the last 6 meetings. The Over cashed in both teams' Week 1 games. This should be high-scoring.
BET OVER 51 (-110).
Best prop bet
Cowboys RB Javonte Williams OVER 2.5 receptions (+110)
Williams had 5 receptions in Week 1. While he had only had 1 game in his final 10 last season with at least 3 catches, he had 3 or more in 3 of his first 4 games and 4 of his first 6 last season.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Washington Commanders at Dallas Cowboys odds, picks and predictions
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