The Minnesota Vikings (1-0) and Chicago Bears (1-0) meet in Week 2 for a NFC North clash Sunday in Chicago, Illinois. Kickoff from Soldier Field is at 1 p.m. ET (FOX). Let's analyze NFL odds around the Vikings vs. Bears odds and make our expert NFL picks and predictions for the best bets.
Minnesota opened the season with a 39-22 win over the Green Bay Packers last Sunday, covering as a 2.5-point home favorite while the Over (45.5) cashed. QB Carson Wentz stepped in after QB Kyler Murray suffered a first-quarter concussion and threw 3 touchdowns, including 2 to WR Justin Jefferson. Minnesota’s defense also did its part, forcing 2 turnovers as the Vikings started the season with an impressive divisional win.
Chicago opened the season with plenty
of fireworks, rolling past the Carolina Panthers 59-37 on the road in the highest-scoring season opener in NFL history. The Bears covered as 3.5-point favorites while the Over (47.5) cruised home. Chicago piled up 552 total yards behind QB Caleb Williams, who accounted for 334 total yards and 4 touchdowns. RB D’Andre Swift was just as busy, rushing for 124 yards and 3 scores.
These 2 teams split their series in 2025. The Bears beat the Vikings outright 19-17 as a 2.5-point road underdog with the Under 47.5 cashing in their last head-to-head meeting on Nov. 16, 2025. Minnesota won the most recent meeting in Chicago, 27-24 as a 1.5-point favorite with the Over (43.5) cashing in the 2025 season opener.
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Vikings at Bears odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at noon ET.
- Moneyline (ML): Vikings +180 (bet $100 to win $180) | Bears -220 (bet $220 to win $100)
- Against the spread (ATS): Vikings +4.5 (-110) | Bears -4.5 (-108)
- Over/Under (O/U): 48 (O: -110 | U: -108)
Vikings at Bears injuries
Vikings
- WR Jauan Jennings (personal) out
- QB Kyler Murray (concussion) out
- OT Brian O'Neill (knee) questionable
Bears
- None
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Vikings at Bears picks and predictions
Prediction
Bears 41, Vikings 27
Moneyline
PASS.
I like the Bears (-220) at home but not at these odds. I'll take my wager to the spread.
Against the spread
BET BEARS -4.5 (-108).
Chicago’s offense came out flying in Week 1, piling up 552 total yards against Carolina. The Bears were especially dominant on the ground, rushing for 291 yards and 6 touchdowns.
Minnesota held Green Bay to just 66 rushing yards, but Chicago’s ground game presents a much tougher challenge. Williams can also create problems with his legs if Brian Flores turns up the pressure.
The Vikings also have uncertainty at quarterback after Murray suffered a concussion in the opener. Wentz played well in relief, but facing Chicago on the road should be a tougher assignment. Minnesota has won 6 straight in Chicago but the Bears have the offensive firepower and rushing attack to finally flip that script.
Over/Under
BET OVER 48 (-110).
Chicago looks built to play high-scoring games but last week also allowed Carolina to answer with 37 points and 478 yards. Minnesota has enough weapons to keep that trend going, especially with Jefferson attacking a vulnerable Bears secondary. With Ben Johnson keeping Chicago aggressive, both offenses should have plenty of opportunities to put points on the board.
Best prop bet
Vikings WR Justin Jefferson Anytime Touchdowns (+125).
Jefferson opened the season looking like himself, catching 8 passes for 92 yards and 2 touchdowns against Green Bay. He remains the clear focal point of Minnesota’s passing game and should continue seeing plenty of opportunities near the goal line. Chicago’s defense couldn't stop the Panthers in Week 1, including plenty of damage through the air. Jefferson also has 4 career touchdown catches against the Bears.
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This article originally appeared on Sportsbook Wire: Minnesota Vikings at Chicago Bears odds, picks and predictions
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