The New York Knicks (4-4) and Cleveland Cavaliers (5-4) meet Saturday from Rocket Arena in Cleveland, Ohio (NBA TV). Tip in the Eastern Conference clash is set for 8 p.m. ET. Let's analyze NBA odds around the Knicks vs. Cavaliers odds and make our expert NBA picks and predictions for the best bets.
2025-26 season series: Knicks won 2-1 in regular season; Knicks won 4-0 in playoffs
The Knicks beat the Chicago Bulls 135-105 Wednesday, covering as an 11.5-point home favorite with the Over (233.5) hitting. New York was led by G Jalen Brunson, who tallied 33 points on 10-for-17 shooting. The Knicks, who are the defending NBA Champions, lost their first 3 games and have won 4 of their last 5 contests. They are 2-6 against the spread (ATS) on the season.
The Cavaliers throttled the Philadelphia 76ers 119-95 Friday, covering as a 2.5-point home underdog. The Under (232.5) cashed. G Donovan Mitchell scored a team-high 23 points and chipped in 8 assists and 7 rebounds. Cleveland snapped its 2-game losing streak with the victory. It is 1-2 ATS in its last 3 games and 3-6 ATS on the season.
Watch the NBA on Fubo!
Knicks at Cavaliers odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:10 p.m. ET.
- Moneyline (ML): Knicks -210 (bet $210 to win $100) | Cavaliers +170 (bet $100 to win $170)
- Against the spread (ATS): Knicks -5.5 (-102) | Cavaliers +5.5 (-118)
- Over/Under (O/U): 223.5 (O: -110 | U: -110)
Knicks at Cavaliers key injuries
Knicks
- F Josh Hart (ankle) out
Cavaliers
(Not yet submitted -- below was for Friday's game)
- C Jarrett Allen (knee) quetsionable
- F Peyton Watson (hamstring) questionable
For most recent updates: Official NBA injury report.
Knicks at Cavaliers picks and predictions
Prediction
Knicks 118, Cavaliers 115
Moneyline
PASS.
No interest; the Cavaliers (+170) have some value as a sizable home underdog. The preferred route is to take the home side on the spread.
Against the spread
BET CAVALIERS +5.5 (-118).
The Knicks as a slight favorite haven't rewarded bettors often this season. They've been favored between 0.5 and 6.5 in 5 of their 8 games and are just 1-4 ATS in those outings. New York is 0-3 ATS on the road as well.
The Cavaliers offense has been consistent enough to trust here. They have scored at least 111 points in 8 straight games and are 2-1 ATS in their previous 3 home contests.
Over/Under
BET OVER 223.5 (-110).
With Hart out, the Knicks defense should take a hit, and that comes at a time when the Cavaliers are figuring things out offensively.
Cleveland has tallied at least 116 points in 2 straight games while allowing a minimum of 117 points in 2 of its last 3 contests. New York is 2-2 O/U in its last 4 games and is coming off its best performance of the season in a 135-point effort against Chicago.
Betting odds calculator
For more sports betting picks and tips, check out SportsbookWire.com and BetFTW. Follow SportsbookWire on X at SportsBookWire and on Facebook.
Access more NBA coverage:
HoopsHype | Celtics Wire | Lakers Wire | Nets Wire | Rockets Wire | Sixers Wire | Thunder Wire | Warriors Wire | Rookie Wire | List Wire
This article originally appeared on Sportsbook Wire: New York Knicks at Cleveland Cavaliers odds, picks and predictions
Advertiser disclosure: USA TODAY may earn a commission when you sign up through links on this page. Commissions never influence our editorial coverage or rankings. Offers and odds were accurate at publication and are subject to change; terms apply — see the operator’s site. This is general information, not betting, legal or financial advice. To the fullest extent permitted by law, USA TODAY is not liable for losses arising from your use of it.
Must be 21+ (18+ where permitted). Sports betting and casino gaming are not legal everywhere; complying with the laws where you are located is your responsibility. Gamble only with funds you can afford to lose. Gambling problem? Help is available 24/7 — call or text 1-800-GAMBLER, or call the National Problem Gambling Helpline at 1-800-MY-RESET. State helplines and responsible gaming resources.













