The Tennessee Titans (0-5) and Indianapolis Colts (2-3) meet Sunday in Indianapolis, Indiana, for a Week 6 battle. Kickoff from Lucas Oil Stadium is at 1 p.m. ET (FOX). Let's analyze NFL odds around the Titans vs. Colts odds and make our expert NFL picks and predictions for the best bets.
Tennessee's rough start continued in Week 5 with a 26-3 loss to their AFC South rival Houston Texans, keeping the Titans winless. Tennessee failed to cover as a 6.5-point home underdog, while the game stayed under the (37.5) total. The Titans managed just 187 yards of offense and committed 2 turnovers. Head coach Robert Saleh remained optimistic, saying, "One game is not going to define us. We're going to continue to work."
Indianapolis remains winless on the
road after falling 34-22 to the Pittsburgh Steelers in Week 5. The Colts failed to cover as 2.5-point road underdogs, while the game cleared the (41.5) total. K Spencer Shrader provided much of the offense, connecting on all 5 field goal attempts, including a 57-yarder. TE Tyler Warren led the offense with 7 catches for 83 yards and a 1-yard touchdown run.
Indianapolis has dominated Tennessee lately, winning 6 straight meetings. The Colts swept last season's series, covering the spread in both games while outscoring the Titans by a whopping 79-34 margin.
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Titans at Colts odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 12:15 p.m. ET.
- Moneyline (ML): Titans +270 (bet $100 to win $270) | Colts -325 (bet $325 to win $100)
- Against the spread (ATS): Titans +7 (-115) | Colts -7 (-102)
- Over/Under (O/U): 44.5 (O: -110 | U: -108)
Titans at Colts injuries
Titans
- DT Jordan Elliott (personal) out
- RB Tyjae Spears (knee) questionable
- CB Joshua Williams (pec) questionable
- S Kevin Winston Jr. (quad) out
Colts
- LB Jaylon Carlies (ribs) out
- WR Ashton Dulin (hamstring) out
- TE Tyler Warren (groin) questionable
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Titans at Colts picks and predictions
Prediction
Colts 27, Titans 13
Moneyline
PASS.
I think the Colts (-325) win the game but I'm not betting these odds. I'll take my bet to the spread.
SUNDAY NIGHT FOOTBALL: Best prop bets
Against the spread
BET COLTS -7 (-102).
Indianapolis has a great opportunity to bounce back Sunday against a Tennessee team that continues to struggle offensively. The Titans are 0-5, averaging 11.6 points and 246.4 yards per game -- both worst in the NFL. They've also scored 10 or fewer points in 3 of their 5 games.
The Colts have dominated this AFC South rivalry, winning 6 straight meetings -- including both matchups last season by a combined 79-34 margin.
RB Jonathan Taylor has been especially dangerous against Tennessee, rushing for 218, 102 and 153 yards in his last 3 meetings while totaling 9 touchdowns. Indianapolis averages 24.8 points per game, more than double Tennessee's offensive production. QB Daniel Jones should have opportunities to move the football if the Colts establish their running game.
With Tennessee struggling to sustain drives and Indianapolis returning home, the Colts have a favorable matchup to get back on track.
Over/Under
BET UNDER 44.5 (-108).
Tennessee's offense ranks last in the NFL, averaging just 11.6 points per game, while QB Cam Ward continues to struggle. The Titans also rank 28th in red-zone touchdown efficiency. Both teams are tied for 24th in third-down conversions, making sustained drives difficult. With Indianapolis leaning on Taylor's running game, this AFC South matchup could become a slow-paced, defensive battle.
Best prop bet
COLTS TE TYLER WARREN ANYTIME TOUCHDOWN (+175).
Note: Warren appeared on the injury report as questionable late Friday so monitor his status and any movement on his prop bets prior to kickoff.
Warren has become one of Indianapolis' most reliable offensive weapons, catching 21 passes on 24 targets over his last 3 games. The rookie tight end is especially dangerous near the goal line, playing 96% of snaps inside the 5-yard line and 92% inside the 10. Warren also showed his versatility with a 1-yard rushing touchdown against Pittsburgh last week. With Tennessee's secondary dealing with injuries, Warren should see plenty of opportunities Sunday.
Betting odds calculator
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This article originally appeared on Sportsbook Wire: Tennessee Titans at Indianapolis Colts odds, picks and predictions
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