The Buffalo Bills have only played the New Orleans Saints 12 times throughout NFL history with the most recent game happening in 2021. Though the Saints are a foe not well-known or studied often by the Bills as
a whole, yet they’ll be traveling to Highmark Stadium in Orchard Park, NY to try and salvage their season.
These two teams couldn’t be on further ends of the spectrum. The Bills have a proven quarterback in Josh Allen, an established run game with James Cook, and a defense that steps up and makes big plays when needed. Oh, and they’re also undefeated. The Saints, on the other hand, are a winless organization relying on Spencer Rattler at quarterback, who has yet to win a game as starter and a poor defense to boot.
If you can’t make it to them game, here’s all the information needed to view it from home…
Bills-Saints game details
- Date: Sunday, September 28, 2025
- Time: 1 p.m. EDT
- Location: Highmark Stadium, Orchard Park, NY
- Weather forecast: Clear skies, light wins and temperature around 74 degrees Fahrenheit
- Referee: Land Clark
Bills-Saints TV info
- Television broadcast: CBS
- Announcers: Andrew Catalon (play-by-play), Charles Davis and Jason McCourty (color analysts), A.J. Ross (sideline reporter)
Bills-Saints streaming info
- Streaming: Fubo TV, Sunday Ticket with YouTube TV, Hulu + Live TV, Sling, Paramount +
- Online: NFL+ (subscription required) if local
Bills-Saints radio info
- Radio broadcast: WGR 550 AM (Buffalo)WCMF 96.5 FM and WROC 950 AM (Rochester)Syracuse (WTKW 99.5/WTKV 105.5)Binghamton (WDRE 100.5FM)Ithaca (WIII 99.9/100.3 FM)Bath (WVIN 98.3 FM)Newark (WACK 1420 AM)Dansville (WDNY 93.9 FM)Elmira (WNGZ 1490 AM)Auburn (WAUB 98.1 FM/1590 AM)Geneva (WGVA 95.9 FM, 1240 AM) — and the rest of the Buffalo Bills Radio Network affiliate stations
- Radio broadcast team: Chris Brown (play-by-play)Eric Wood (analyst)Sal Capaccio (sideline reporter)
- Satellite radio: SiriusXM — 227 (Bills feed) / Ch 382 (Ravens feed)
Bills-Saints betting line
- Betting Line: Bills -14.5
- Over/Under: 48.5
- Money line: Bills -1500, Saints +870
- More odds: FanDuel Sportsbook
Buffalo Rumblings social media
- Twitter: @BuffRumblings
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- Saints on SB Nation: Canal Street Chronicles
