We’re getting to them a little later than usual, but it’s time for our staff of learned pro football diehards to reveal our picks for Week 16 of the 2025 NFL season. I was hoping to get these out there before Saturday’s games, but a few things happened and I was unable to do so. But, they’re here for your viewing pleasure now, so let’s get to them, shall we?
First, as always, we’ve got our look at how our picks are going so far this season. You can take a look at how we’re doing in any of the categories
we make picks in for any given week, or for the season as a whole.
With that, here are our picks for this week. As always, we remind you that the numbers for some of our selections, such as over/unders and picks against the spread, may be different for each selector based on when they punched their picks into the system that our friends at Tallysight have provided for us. If you’re planning on putting any sort of wagers down on this week’s games, be sure to check with your sportsbook of choice.
Unanimous Picks
- Buffalo Bills over Cleveland Browns
- New Orleans Saints over New York Jets
- Minnesota Vikings over New York Giants
- Houston Texans over Las Vegas Raiders
- San Francisco 49ers over Indianapolis Colts
- Los Angeles Rams over Seattle Seahawks (everyone gets it wrong)
- Philadelphia Eagles over Washington Commanders (everyone gets it right)
4-1 Picks
- Los Angeles Chargers over Dallas Cowboys (Eric dissenting)
- Kansas City Chiefs over Tennessee Titans (GA Skol dissenting)
- Cincinnati Bengals over Miami Dolphins (Sam dissenting)
- Denver Broncos over Jacksonville Jaguars (GA Skol dissenting)
- Atlanta Falcons over Arizona Cardinals (Shawn dissenting)
- Detroit Lions over Pittsburgh Steelers (Shawn dissenting)
3-2 Picks
- Green Bay Packers over Chicago Bears (Chris and Sam dissenting)
- Tampa Bay Buccaneers over Carolina Panthers (GA Skol and Shawn dissenting)
- New England Patriots over Baltimore Ravens (Chris and Shawn dissenting)
Those are the picks for this week, folks! Who are you rolling with in Week 16 of NFL action?









