Today, the Cleveland Browns take on the Buffalo Bills in Week 16 of the 2025 NFL season. The Browns (3-11) are full of injuries, and after last week’s lifeless game against the Bears, do they have any hope in front of the home crowd? Once again, I find myself cheering for good individual efforts from QB Shedeur Sanders and DE Myles Garrett, but don’t really expect or care about anything else. The Bills (10-4) have some flaws, but are coming off a big comeback win over the Patriots and have that degree
of explosiveness that Cleveland’s defense doesn’t seem up to stopping now.
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Here are some features we’ve had this week to help preview the game:
- Browns NFL draft Week 16 rooting guide: Injuries to former contenders should help move CLE up
- Keys for the Browns defense in limiting the Bills offense
- Cleveland Browns vs. Buffalo Bills Week 16 Predictions – It’s not going to be pretty
- Browns vs. Bills: Week 16 Need to Know
- Browns line, QB play dramatically hurting RB Quinshon Judkins’ performance
- NFL head coach carousel: Browns job ranked near top of potential options if Stefanski fired
This is your game thread to discuss the first quarter of the game, so be sure to participate in the comments section below. As always, GO BROWNS!
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Game: Buffalo Bills vs. Cleveland Browns
Date/Time: Sunday, December 21, 2025 at 1:00 PM ET
Local Television: CBS – Ian Eagle (play-by-play) & J.J. Watt (analyst)
Local Radio: ESPN 850 WKNR, 92.3 The Fan, 98.5 FM WNCX
