The Indianapolis Colts host the San Francisco 49ers in Indy. These teams are on vastly different trajectories, as the Niners are on a four-game winning streak and Indy is on a four-game losing streak.
Will San Francisco make it five-straight? Can Indy avoid five-straight? Let’s tune in to find out!
San Francisco 49ers at Indianapolis Colts
Lucas Oil Stadium – Indianapolis, Indiana
Kickoff – 5:15pm PST / 7:15pm CST / 8:15pm EST
Network – ESPN
Odds – 49ers -5.5, O/U 46.5
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