It is time once again.
For the Arizona Cardinals, they have a chance to get back into the win column in the NFC West, and keep their ever slimming playoff hopes alive.
For the San Francisco 49ers, it is about
getting their stars on offense back and looking to keep their pace in the NFC, that allows them to have a chance to make the playoffs once again.
It is a big game for both sides, can the Arizona Cardinals put together a game that gives them a chance?
Week 11: Arizona Cardinals (3-6) vs San Francisco 49ers (6-4)
Date: Sunday, November 16, 2025
Time: 2:05 p.m. AT
Location: State Farm Stadium — Glendale, AZ
National TV: Fox (Channel 10 locally)
National online streaming: NFL+, FoxSports Streaming
TV announcers: Kevin Kugler (play-by-play) Daryl Johnston (analyst) Allison Williams (sideline)
Radio: Arizona Sports 98.7 FM
Radio announcers: Dave Pasch (play-by-play), A.Q. Shipley (analyst) and Paul Calvisi (sideline)
Spanish Radio: Fuego Radio 106.7 FM
Spanish Radio announcers: Luis Hernandez (play-by-play) and Irving Villanueva (analyst)
Betting line: Cardinals +3 per FanDuel Sportsbook
