Gameweek 28 of the Premier League arrives at a crucial stage of the season, where title ambitions, European dreams and relegation fears all hang in the balance.
With several key players nursing injuries and others racing against time to prove their fitness, team news could once again play a decisive role in shaping the weekend’s results.
In this article, we round up the latest injury updates across the division and offer score predictions for every fixture as the drama of the run-in continues to intensify.
Wolverhampton Wanderers vs Aston Villa (20:00)
Wolverhampton Wanderers have just one confirmed absentee at the moment.
Hee-Chan Hwang remains sidelined with a calf issue and is currently limited to individual training, meaning he will not be available for the upcoming fixture.
Aston Villa are facing a significant injury setback. Boubacar Kamara is expected to miss the rest of the season, while Youri Tielemans and John McGinn are set for extended spells out.
Harvey Elliott and Alysson also remain unavailable through injury, and Marco Bizot is suspended following a red card — leaving Villa stretched across multiple areas of the squad.
Prediction: Wolves 1-1 Aston Villa
AFC Bournemouth vs Sunderland (12:30)
AFC Bournemouth currently have three confirmed absentees. Justin Kluivert faces a lengthy spell out following knee surgery, while Ben Gannon-Doak is also sidelined after undergoing a procedure for a hamstring injury.
Julio Soler remains unavailable as he continues to recover from a recent setback, leaving Bournemouth with limited options in certain areas.
Sunderland have three injury concerns at the moment. Reinildo Mandava is set to miss around four weeks with a knee issue, while Bertrand Traoré remains unavailable but could return to training soon.
Dennis Cirkin has also picked up a minor hamstring problem and will be assessed ahead of the next fixture.
Prediction: Bournemouth 2-0 Sunderland
Burnley vs Brentford (15:00)
Burnley are continuing to struggle with a lengthy injury list. Josh Cullen remains a long-term absentee after his ACL injury, while Connor Roberts is also set for an extended spell out.
Zeki Amdouni, Axel Tuanzebe, and Armando Broja are all sidelined, with Broja expected back in a couple of weeks.
Jordan Beyer and Mike Trésor also remain unavailable, leaving Burnley stretched across several positions. Brentford continue to deal with several absentees.
Fábio Carvalho and Antoni Milambo remain long-term knee injury concerns, while Josh Dasilva is still working his way back with no confirmed return date.
Michael Kayode is a doubt after picking up a knock in training, and Aaron Hickey is also being assessed, leaving Brentford with limited defensive depth heading into the next fixture.
Prediction: Burnley 1-2 Brentford
Liverpool vs West Ham United (15:00)
Liverpool are managing a growing injury list. Conor Bradley and Giovanni Leoni remain long-term absentees with knee injuries, while Wataru Endo is also expected to be out for an extended period.
Alexander Isak is progressing but still some way from full match fitness. There is hope that Jeremie Frimpong could return soon pending assessment, and Florian Wirtz is being monitored after a back issue forced him out during warm-up.
West Ham United have three confirmed absentees. Freddie Potts is suspended following a red card, Pablo Felipe Pereira de Jesus remains sidelined with a calf injury but is improving, and Łukasz Fabiański continues to miss out due to a back problem with no clear return date.
Prediction: Liverpool 1-0 West Han United
Newcastle United vs Everton (15:00)
Newcastle United have been hit hard by injuries at a crucial stage of the season. Emil Krafth looks set to miss the remainder of the campaign after knee surgery, while Bruno Guimarães and Fabian Schär are also facing lengthy spells out.
Valentino Livramento and Lewis Miley remain sidelined but are edging closer to early March returns.
There is some positive news, however, with Yoane Wissa and Sven Botman both nearing a comeback pending late fitness checks. Everton have just two confirmed absentees.
Jack Grealish is set for a long spell out after undergoing ankle surgery, while Jake O’Brien is suspended following a red card and will miss the upcoming fixture.
Prediction: Newcastle United 1-1 Everton
Leeds United vs Manchester City (17:30)
Leeds United have a single confirmed absentee at the moment.
Noah Okafor is sidelined with a hamstring injury and is expected to miss the next few weeks, ruling him out of the upcoming fixtures against Aston Villa and Manchester City.
Manchester City have four players currently unavailable or doubtful. Mateo Kovačić and Joško Gvardiol remain long-term absentees, with City still light defensively.
Max Alleyne is being assessed after a knock, while Jeremy Doku is not yet ready to return as he continues his recovery from a calf issue.
Prediction: Leeds United 1-2 Manchester City
Brighton & Hove Albion vs Nottingham Forest (14:00)
Brighton still have two long-term absentees in Stefanos Tzimas and Adam Webster following serious knee injuries.
There is more encouraging news elsewhere, with James Milner passed fit and available, while Yasin Ayari and Solly March are both edging closer to returns and could feature pending late fitness checks.
On the other hand, Nottingham Forest are dealing with five injury concerns.
John Victor and Chris Wood remain sidelined with knee issues, while Nicolò Savona is still undergoing assessment to determine the extent of his problem.
Matz Sels is recovering from a groin injury and working towards a return, and Willy Boly continues his rehabilitation after struggling with a knee issue, leaving Forest short of options in key areas.
Prediction: Brighton 3-1 Nottingham Forest
Fulham vs Tottenham Hotspur (14:00)
Fulham have a few fitness concerns heading into the next fixture.
Samuel Chukwueze is expected to miss out with a minor calf issue but could return soon, while Antonee Robinson is also a doubt after struggling with an ankle problem.
Saša Lukić is back involved in training but will need assessment, and there is uncertainty over Kevin Santos Lopes de Macedo, whose issue is still being evaluated.
Meanwhile, Tottenham Hotspur are facing a major injury crisis with a lengthy list of absentees.
Wilson Odobert has suffered an ACL rupture, while James Maddison, Dejan Kulusevski, Rodrigo Bentancur, Mohammed Kudus, Ben Davies, and Destiny Udogie are all ruled out with significant injuries.
Cristian Romero is suspended, and Lucas Bergvall remains sidelined.
There is some positive news, however, with Micky van de Ven, Pedro Porro, and Kevin Danso all passed fit and available for selection, offering a slight boost amid an otherwise challenging situation.
Prediction: Fulham 2-2 Tottenham
Manchester United vs Crystal Palace (14:00)
Manchester United have four injury concerns at the moment. Patrick Dorgu Larsson faces a spell on the sidelines with a thigh issue, while Matthijs de Ligt remains out as he continues his recovery.
Mason Mount is edging closer to a return but is still being assessed, and Lisandro Martínez is also a doubt after picking up a minor calf problem during the week.
At the moment, Crystal Palace have several key players sidelined. Cheick Doucouré and Eddie Nketiah remain long-term absentees, while Jean-Philippe Mateta and Jefferson Lerma are also ruled out for the coming weeks with knee and hamstring issues, respectively.
There is some cautious optimism around Maxence Lacroix, who has returned to training and faces a late fitness test ahead of the next fixture.
Prediction: Manchester United 2-0 Crystal Palace
Arsenal vs Chelsea (16:30)
Match of the week! Arsenal have several injury concerns to manage. Mikel Merino faces a lengthy spell out as he recovers from ankle surgery, while Max Dowman also remains unavailable.
Kai Havertz and Ben White are both doubts and will be assessed closer to kick-off, and Bukayo Saka is nearing a return but is still being monitored following an ankle sprain.
On the other hand, Chelsea are contending with a lengthy injury and suspension list. Levi Colwill remains on the comeback trail after knee surgery, while Jamie Bynoe-Gittens and Marc Cucurella are sidelined with hamstring injuries.
Wesley Fofana and Mykhailo Mudryk are unavailable due to suspension, and Filip Jorgensen plus Dário Essugo are still not ready to return.
Romeo Lavia is being eased back due to fitness concerns, and there is fresh uncertainty over Estevão, who is undergoing scans after feeling discomfort in his hamstring.
Prediction: Arsenal 3-0 Chelsea
