We’ve got one game left for Week 12 of the 2025/’26 NFL season. This week’s Monday Night Football features the Carolina Panthers visiting the San Francisco 49ers. The Panthers have been better than expected
this season, and are only a game behind the Niners in the NFC. They are half a game behind the Buccaneers in the NFC South, while San Francisco is sitting in 3rd place in the NFC West. Big game for both teams looking to make a playoff run this year.
Who: Carolina Panthers (6-5) at San Francisco 49ers (7-4)
Where: Levi’s Stadium | Santa Clara, CA
When: November 24, 2025, 8:15 p.m.
TV: ABC/ESPN
Joe Buck (play-by-play)
Troy Aikman (analyst)
Lisa Salters (sideline)
ManningCast on ESPN2
Sirius XM NFL
Carolina: XM/SXM 226, Internet 804
San Francisco: XM/SXM 225, Internet 827
National: 88
Español: XM/SXM 227, Internet 832
FanDuel Sportsbook odds: 49ers -7.5, 49.5 O/U
Carolina: +320
San Francisco: -405
Prediction: 49ers 33 – Panthers 20
SB Nation Blogs: Cat Scratch Reader | Niners Nation
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