Pick’em Podcast Week 2: Will Michigan Football (+4.5) upset Oklahoma?

Michigan quarterback Bryce Underwood (19) is tackled by New Mexico defensive tackle Xavier Slayton (15) during the second half at Michigan Stadium in Ann Arbor on Saturday, August 30, 2025.

Von Lozon and Kellen Voss are back with another edition of the Pick’em Podcast. While there aren’t many marquee matchups this weekend outside of Michigan vs Oklahoma, there are a ton of interesting games to wager on. The Michigan State Spartans are favored against Boston College at home, Illinois is a slight road favorite at Duke, and Florida is a three-score favorite over Group of 5 CFP hopeful USF.

All odds courtesy of DraftKings Sportsbook. Please gamble responsibly.

No. 11 Illinois (-3) at Duke

Boston College at Michigan State (-4.5) No. 20 Ole Miss (-10) at Kentucky No. 12 Arizona State (-6.5) at Mississippi State Kansas at Missouri (-6.5) South Florida at No. 13 Florida (-17.5) Iowa at No. 16 Iowa State (-3) No. 15 Michigan at No. 18 Oklahoma (-4.5)