Bo Nix and the visiting Denver Broncos wiped out a 14-point fourth-quarter deficit and snapped Philadelphia's 10-game winning streak with a 21-17 victory on Sunday.
After punting on seven of their first eight drives, the Broncos (3-2) scored touchdowns on back-to-back possessions to seize the lead. J.K. Dobbins made it 17-10 with a 2-yard TD run with 13:11 remaining, and Nix put Denver ahead with an 11-yard TD pass to Evan Engram and a gutsy two-point conversion toss to Troy Franklin with 7:36 left.
The defending Super Bowl champion Eagles (4-1) also had a 12-game home winning streak snapped, dating back to Week 2 of last season. Nix passed for 242 yards and improved his career record to 5-1 against NFC opponents. Courtland Sutton caught eight passes for 99 yards and Dobbins ran for 79 yards.
Philadelphia's Jalen Hurts passed for a season-high 280 yards and threw touchdowns to Saquon Barkley and Dallas Goedert, but he was also sacked six times.
Titans 22, Cardinals 21
Joey Slye booted a 29-yard field goal on the final play to cap Tennessee's rally from a 21-6 fourth-quarter deficit in Glendale, Ariz., to claim its first win.
Cam Ward, who completed 21 of 39 passes for 265 yards, directed the Titans (1-4) on a 71-yard drive in the final two minutes to set up Slye's game-winner. Tony Pollard rushed for a 1-yard score to start the Titans' comeback, then Tyler Lockett recovered a loose ball for a score with 4:39 left on a wild play that began with Ward throwing an interception to the 5-yard line that the Cardinals fumbled, kicked and poked into the end zone.
Kyler Murray completed 23 of 31 for 220 yards for the Cardinals (2-3), who held a 21-3 lead early in the second quarter on rushing scores by Michael Carter, Murray and Bam Knight. Emari Demercado thought he broke away for a 72-yard touchdown run with 12:40 left that would have made it 27-6, but he deliberately let the ball drop inches before crossing the goal line.
Texans 44, Ravens 10
C.J. Stroud passed for 244 yards and four touchdowns, and Houston rode a dominating defensive performance to a road victory over injury-plagued Baltimore.
Jalen Pitre snagged two interceptions for the Texans (2-3) and Stroud was exceedingly efficient, completing 23 of 27 attempts while benefiting from solid pass protection. Xavier Hutchinson and rookie Jaylin Noel each recorded their first career scoring receptions, with Hutchinson adding a second touchdown catch just before halftime.
Derrick Henry finished with 33 yards on 15 carries for the Ravens (1-4) and scored their lone touchdown on a 1-yard run late in the third quarter. Cooper Rush passed for 179 yards and tossed three interceptions in place of two-time MVP Lamar Jackson, who was out with a hamstring injury.
Vikings 21, Browns 17
Carson Wentz threw a 12-yard touchdown pass to Jordan Addison with 25 seconds left in regulation, lifting Minnesota to a win over Cleveland in London.
Wentz completed 25 of 34 passes for 236 yards and a touchdown for Minnesota (3-2), which bounced back from a loss to the Pittsburgh Steelers in Dublin last week. Justin Jefferson had seven catches for 123 yards, and Addison tallied five catches for 41 yards despite being benched at times for what was referred to as a coach's decision.
Quinshon Judkins had 23 carries for 110 yards for the Browns (1-4). Fellow rookie Dillon Gabriel made his first career start at quarterback and completed 19 of 33 passes for 190 yards and two touchdowns.
Colts 40, Raiders 6
Jonathan Taylor rushed for three touchdowns and Daniel Jones threw for two more as Indianapolis blasted visiting Las Vegas.
Jones completed 20 of 29 passes for 212 yards for Indianapolis (4-1), which bounced back from a Week 4 loss at the Los Angeles Rams by scoring 40 consecutive points in the middle two quarters. This included three touchdowns -- two by Taylor -- in a span of less than 4 1/2 minutes in the third quarter.
Geno Smith hit 25 of 36 passes for 228 yards and two interceptions for the Raiders (1-4), who lost their fourth straight game. Rookie Ashton Jeanty rushed 14 times for 67 yards for Las Vegas, which was blown out despite the Colts' modest 317-296 edge in total yards.
Panthers 27, Dolphins 24
Bryce Young threw for two touchdowns and Rico Dowdle ran for 206 yards and a touchdown as Carolina rallied past Miami in Charlotte.
Young's 4-yard pass to rookie tight end Mitchell Evans with 1:59 to play gave the Panthers (2-3) the lead for good as they matched the largest comeback to win a game in franchise history by overcoming a 17-point hole. Dowdle, filling in for injured Chuba Hubbard, came up 4 yards shy of matching the single-game franchise rushing record.
Miami's Tua Tagovailoa completed 27 of 36 throws for 256 yards with three touchdowns and Jaylen Waddle gained 110 receiving yards on six catches and scored a touchdown, but the Dolphins (1-4) dropped to 0-3 in road games.
Cowboys 37, Jets 22
Dak Prescott passed for 237 yards and a season-high four touchdowns to help Dallas roll to a victory over woeful New York at East Rutherford, N.J.
Javonte Williams rushed for 135 yards and one touchdown and also had a scoring reception, and Jake Ferguson caught two scoring passes for the Cowboys (2-2-1). George Pickens caught a touchdown pass and Ryan Flournoy had six receptions for 114 yards for Dallas, which scored 30 straight points after falling behind 3-0 with a pair of touchdowns in the final minute of the first half.
Justin Fields was 32-of-46 passing for 283 yards and two touchdowns as the Jets became the first team in NFL history to start 0-5 without forcing a single turnover. Breece Hall rushed for 113 yards but lost a key fumble. Garrett Wilson and Andrew Beck caught touchdown passes from Justin Fields, who threw for 283 yards.
Saints 26, Giants 14
Spencer Rattler threw an 87-yard touchdown pass, Kool-Aid McKinstry recorded two interceptions, Jordan Howden returned a fumble 86 yards for a touchdown and host New Orleans beat New York to give rookie head coach Kellen Moore his first victory.
Rattler completed 20 of 30 passes for 225 yards, and the Saints (1-4) won for the first time in his 11 starts over his two-year career.
Rookie Jaxson Dart completed 26 of 40 for 202 yards with two touchdowns and two interceptions for the Giants (1-4), who turned the ball over five times and did not force any turnovers.
Buccaneers 38, Seahawks 35
Chase McLaughlin kicked three field goals, including a 39-yarder as time expired, to give Tampa Bay a victory against host Seattle.
Baker Mayfield completed 29 of 33 passes for 379 yards and two touchdowns for the Buccaneers (4-1). He hit Sterling Shepard with an 11-yard scoring strike with 1:08 remaining to tie the score at 35. Tampa Bay got the ball back on Lavonte David's interception on a ball that deflected off the helmet of teammate Logan Hall at the line of scrimmage to set up the winning kick.
Sam Darnold was 28-of-34 passing for 341 yards, four TDs and two interceptions for the Seahawks (3-2), who had a three-game winning streak snapped. AJ Barner caught two scoring passes for Seattle.
Lions 37, Bengals 24
David Montgomery tossed a touchdown pass and ran for another in his return to his hometown as Detroit hung on to beat host Cincinnati.
Montgomery, a running back, threw a 3-yard option pass to tight end Brock Wright in the second quarter and ran 8 yards for a touchdown in the third quarter. Detroit quarterback Jared Goff completed 19 of 23 passes on the day for 258 yards and three touchdowns.
The Lions (4-1) were rolling to their fourth straight blowout win before the Bengals (2-3) made it close with Jake Browning's three fourth-quarter touchdown passes. Two went to Ja'Marr Chase, who finished with six catches and 110 yards; he also made three tackles on the day, bringing down the defender after all three Browning interceptions.
Commanders 27, Chargers 10
Rookie Jacory Croskey-Merritt rushed for 111 yards and two scores, Jayden Daniels passed for 231 yards and a touchdown in his return to the lineup and Washington rallied from a 10-point deficit against Los Angeles in Inglewood, Calif.
Daniels, who missed the previous two games with a left knee injury, completed 15 of 26 passes and ran for 39 yards. Deebo Samuel had eight catches for 96 yards and a touchdown for Washington (3-2), which scored the final 27 points of the game.
Justin Herbert completed 22 of 29 passes for 166 yards, one touchdown and one interception for the Chargers (3-2), who have lost two straight. Keenan Allen caught five passes, giving him 1,003 career receptions in 159 games. He became the fastest player in NFL history to reach the 1,000-catch mark, breaking the record owned by Marvin Harrison Sr.
--Field Level Media
