Week 10 of the college football schedule might be Christmas in November for fans across the nation.
It features not only seven games between teams ranked in the latest US LBM Coaches Poll, but also two among teams ranked in the top 10: No. 1 Miami at No. 6 Notre Dame, and No. 8 BYU at No. 4 Utah.
The former game, of course, received the "College GameDay" designation of the week, not only for the teams' statuses as historical rivals, but also for the brand power and College Football Playoff implication from the game. That's especially true after a controversial final top 25 in the CFP rankings last year: Despite the Fighting Irish ranking ahead of the Hurricanes all season, the selection committee placed the Hurricanes ahead of the Irish, booting
Marcus Freeman's squad from the playoff.
Surely that won't come up again on Saturday, Nov. 7.
In Salt Lake City, the Utes and Cougars will aim for Big 12 supremacy. BYU has been subject to several controversial calls over the past three weeks, but it can put all of that to bed with a win at its most hated rival's house.
Elsewhere, No. 2 Georgia will travel to take on Trinidad Chambliss and 12th-ranked Mississippi. The two teams had two incredible meetings in 2025, with the Rebels getting one back over Kirby Smart's Bulldogs in the CFP quarterfinal game — and without Lane Kiffin, to boot.
Speaking of the LSU coach, he will look to lead his 15th-ranked Tigers to a home win over Kalen DeBoer and visiting, ninth-ranked Alabama in a game with massive SEC and CFP implications. The Crimson Tide and Tigers both have two losses, and another could jeopardize either team's playoff hopes.
Finally, in the Big Ten, No. 23 Northwestern will look to come back from a gutting loss to Oregon with a home game over No. 20 Iowa, fresh off thrashing Wisconsin, 30-0.
College football Week 10 top-25 predictions, picks
Odds courtesy of BetMGM as of Monday, Nov. 2
No. 1 Miami at No. 6 Notre Dame
- Spread: Notre Dame (-5)
- Over/under: 57.5 points
- Moneyline: Notre Dame (220-) | Miami (+180)
- Craig Meyer: Notre Dame 31, Miami 30
- Austin Curtright: Notre Dame 27, Miami 24
- John Leuzzi: Miami 24, Notre Dame 17
- Jordan Mendoza: Miami 29, Notre Dame 24
- Adam Bittner: Miami 35, Notre Dame 24
What our experts think: "Notre Dame needs this win for its College Football Playoff hopes. The Fighting Irish are running out of opportunities for signature wins, and are also seeking revenge after losing to Miami last season (which ultimately kept them out of the field). Those reasons — plus, Notre Dame playing at night in South Bend — give the Irish the edge. " — Austin Curtright, USA TODAY
No. 2 Georgia at No. 12 Ole Miss
- Spread: Georgia (-3.5)
- Over/under: 56.5 points
- Moneyline: Georgia (-175) | Ole Miss (+145)
- Craig Meyer: Georgia 34, Ole Miss 23
- Austin Curtright: Georgia 30, Ole Miss 21
- John Leuzzi: Georgia 28, Ole Miss 24
- Jordan Mendoza: Georgia 38, Ole Miss 27
- Adam Bittner: Georgia 31, Ole Miss 21
What our experts think: "The Bulldogs' loss to Auburn may well end up being the most bizarre result of the season. This is a team with an efficient offense and a characteristically nasty defense that looks like maybe the best all-around squad in the country. Not even Trinidad Chambliss' heroics will be enough to overcome that." — Craig Meyer, USA TODAY
No. 8 BYU at No. 4 Utah
- Spread: Utah (-5.5)
- Over/under: 48.5 points
- Moneyline: Utah (-210) | BYU (+170)
- Craig Meyer: Utah 27, BYU 20
- Austin Curtright: BYU 28, Utah 24
- John Leuzzi: Utah 27, BYU 24
- Jordan Mendoza: BYU at Utah 28, BYU 20
- Adam Bittner: Utah 28, BYU 20
What our experts think: "The morning edition of the Holy War is going to lead to a slow start from both sides, but the offenses are going to make for a fun second half. The Cougars are too hit-or-miss while the Utes are excellent on both sides of the ball. Home-field advantage comes up big to keep Utah undefeated." — Jordan Mendoza, USA TODAY
No. 5 UCLA at Minnesota
- Spread: UCLA (-5.5)
- Over/under: 39.5 points
- Moneyline: UCLA (-220) | Minnesota (+180)
- Craig Meyer: Minnesota 20, UCLA 17
- Austin Curtright: Minnesota 24, UCLA 20
- John Leuzzi: UCLA 31, Minnesota 14
- Jordan Mendoza: Minnesota 16, UCLA 13
- Adam Bittner: Minnesota 24, UCLA 20
What our experts think: "Minnesota nearly took down a top-10 team in Week 9, but opportunity awaits in Week 10. UCLA’s offense has been lagging recently, and the Golden Gophers defense is going to cause all sorts of problems. It’s another low-scoring affair, but a late field goal does it for the Gophers to shake up the CFP picture." — Jordan Mendoza, USA TODAY
No. 7 Kentucky at No. 16 Tennessee
- Spread: Tennessee (-6.5)
- Over/under: 50.5 points
- Moneyline: Tennessee (-235) | Kentucky (+200)
- Craig Meyer: Kentucky 24, Tennessee 21
- Austin Curtright: Tennessee 23, Kentucky 20
- John Leuzzi: Kentucky 28, Tennessee 20
- Jordan Mendoza: Tennessee 26, Kentucky 24
- Adam Bittner: Kentucky 27, Tennessee 17
What our experts think: "Will Stein has Kentucky on the brink of a CFP appearance in just his first season. The Wildcats' path to the SEC doesn't take a step back here as Kenny Minchey and Co. walk into Rocky Top and come out with a top-20 win." — John Leuzzi, USA TODAY
No. 9 Alabama at No. 15 LSU
- Spread: LSU (-5.5)
- Over/under: 52.5 points
- Moneyline: LSU (-220) | Alabama (+180)
- Craig Meyer: Alabama 31, LSU 27
- Austin Curtright: LSU 33, Alabama 24
- John Leuzzi: Alabama 31, LSU 24
- Jordan Mendoza: Alabama 34, LSU 30
- Adam Bittner: LSU 35, Alabama 28
What our experts think: "Tigers quarterback Sam Leavitt was flat out bad in his first three games: He threw three touchdowns and five interceptions against Clemson, Louisiana Tech and Ole Miss. Since then, he has completed 75.4% of his passes and has vastly reduced his turnovers as he’s adjusted to coach Lane Kiffin’s system. Keelon Russell can get just as hot for the Crimson Tide. We just haven’t seen as much of that lately, so we’ll lean toward Leavitt and Co. here." — Adam Bittner, USA TODAY
Oregon at No. 10 Ohio State
- Spread: Ohio State (-7.5)
- Over/under: 48.5 points
- Moneyline: Ohio State (-275) | Oregon (+220)
- Craig Meyer: Ohio State 23, Oregon 17
- Austin Curtright: Ohio State 27, Oregon 17
- John Leuzzi: Oregon 24, Ohio State 20
- Jordan Mendoza: Ohio State 22, Oregon 17
- Adam Bittner: Ohio State 38, Oregon 24
What our experts think: "Is there real concern with Luke Fahey? Ohio State’s offense looked bad against USC, proving Jeremiah Smith can’t just do everything. Oregon showed a semblance of life against Northwestern, but the Buckeyes defense is going to stop any momentum from carrying over in an ugly win for the Buckeyes." — Jordan Mendoza, USA TODAY
No. 11 Texas at No. 19 Missouri
- Spread: Texas (-2.5)
- Over/under: 44.5 points
- Moneyline: Texas (-140) | Missouri (+115)
- Craig Meyer: Texas 27, Missouri 24
- Austin Curtright: Missouri 24, Texas 21
- John Leuzzi: Texas 35, Missouri 21
- Jordan Mendoza: Missouri 27, Texas 24
- Adam Bittner: Missouri 29, Texas 24
What our experts think: "It’s tempting to make this all about whether Arch Manning plays well, because he’s arguably the face of the sport. Running back Jamal Roberts’ numbers for the Tigers are pretty determinative in their own right, though. When they’ve won against FBS competition this season, he’s averaging 164.8 yards per game. When they’ve lost, it's 67. The biggest question therefore becomes whether the Longhorns can take him away or not." — Adam Bittner, USA TODAY
West Virginia at No. 13 Texas Tech
- Spread: Texas Tech (-16.5)
- Over/under: 63.5 points
- Moneyline: Texas Tech (-800) | West Virginia (+600)
- Craig Meyer: Texas Tech 37, West Virginia 27
- Austin Curtright: Texas Tech 38, West Virginia 24
- John Leuzzi: Texas Tech 38, West Virginia 14
- Jordan Mendoza: Texas Tech 33, West Virginia 24
- Adam Bittner: Texas Tech 32, West Virginia 28
What our experts think: "Texas Tech's offense looked improved against Arizona with Tommy Castellanos at quarterback, giving the Red Raiders a better dual-threat option under center. West Virginia's defense is among the worst in the country, and while its offense can score some points, it shouldn't pose a problem for Texas Tech." — Austin Curtright, USA TODAY
Cincinnati at No. 18 Houston
- Spread: Houston (-10.5)
- Over/under: 62.5 points
- Moneyline: Houston (-450) | Cincinnati (+340)
- Craig Meyer: Houston 34, Cincinnati 19
- Austin Curtright: Houston 35, Cincinnati 24
- John Leuzzi: Houston 28, Cincinnati 17
- Jordan Mendoza: Houston 30, Cincinnati 16
- Adam Bittner: Cincinnati 38, Houston 35
What our experts think: "It’s hard for any running back to get meaningfully involved in a game when the opponent scores touchdowns on its first five possessions, as Utah did last week against Cincinnati. Cole Tabb still managed 131 yards on just 14 carries in the loss for the Bearcats and he’s averaging 9.3 yards per carry in his past three games. If Cincinnati can apply any kind of resistance to the Cougars and quarterback Conner Weigman, a more favorable game script could lead to a truly huge day." — Adam Bittner, USA TODAY
No. 20 Iowa at No. 23 Northwestern
- Spread: Northwestern (-2)
- Over/under: 44.5 points
- Moneyline: Northwestern (-135) | Iowa (+110)
- Craig Meyer: Northwestern 26, Iowa 20
- Austin Curtright: Iowa 24, Northwestern 17
- John Leuzzi: Northwestern 21, Iowa 17
- Jordan Mendoza: Iowa 24, Northwestern 21
- Adam Bittner: Northwestern 28, Iowa 14
What our experts think: "This one could be a sneaky good matchup in the Big Ten, as both teams are 6-2 on the season and have the same conference record. Aidan Chiles out-duels Hank Brown and Iowa's defense to continue Northwestern's impressive season." — John Leuzzi, USA TODAY
No. 21 Boise State at Colorado State
- Spread: Boise State (-17.5)
- Over/under: 68.5 points
- Moneyline: Boise State (-900) | Colorado State (+625)
- Craig Meyer: Boise State 52, Colorado State 24
- Austin Curtright: Boise State 45, Colorado State 27
- John Leuzzi: Boise State 45, Colorado State 7
- Jordan Mendoza: Boise State 55, Colorado State 23
- Adam Bittner: Boise State 41, Colorado State 20
What our experts think: "Since a Week 2 win against FCS Southern Utah, the Rams have allowed fewer than 41 points to an opponent only once ... and in that outlier, they gave up 31 points to Utah State in a 17-point loss. It's no wonder their defensive coordinator was relieved of play-calling duties in the middle of a game." — Craig Meyer, USA TODAY
TCU at No. 22 Arizona
- Spread: Arizona (-9.5)
- Over/under: 42.5 points
- Moneyline: Arizona (-350) | TCU (+280)
- Craig Meyer: Arizona 33, TCU 16
- Austin Curtright: Arizona 24, TCU 14
- John Leuzzi: Arizona 28, TCU 14
- Jordan Mendoza: Arizona 35, TCU 22
- Adam Bittner: Arizona 27, TCU 24
What our experts think: "Arizona nearly pulled off an upset against Texas Tech last week on the road. Noah Fifita helps the Wildcats bounce back with a win against a bottom-tier TCU team in the Big 12. Fifita throws for a pair of touchdowns and records his third consecutive game of at least 300 passing yards." — John Leuzzi, USA TODAY
Virginia Tech at No. 24 SMU
- Spread: SMU (-6)
- Over/under: 55.5 points
- Moneyline: SMU (-225) | (+185)
- Craig Meyer: SMU 37, Virginia Tech 27
- Austin Curtright: SMU 31, Virginia Tech 30
- John Leuzzi: SMU 28, Virginia Tech 21
- Jordan Mendoza: SMU 25, Virginia Tech 23
- Adam Bittner: SMU 31, Virginia Tech 21
What our experts think: "The Mustangs haven't lost back-to-back regular-season games since 2022. Coming off a loss to Syracuse last week, expect Kevin Jennings and the high-powered Mustangs to bounce back against a much-improved Hokies squad." — Craig Meyer, USA TODAY
No. 25 New Mexico at Nevada
- Spread: New Mexico (-10)
- Over/under: 38.5 points
- Moneyline: New Mexico (-400) | Nevada (+320)
- Craig Meyer: New Mexico 23, Nevada 13
- Austin Curtright: New Mexico 21, Nevada 13
- John Leuzzi: New Mexico 21, Nevada 14
- Jordan Mendoza: New Mexico 28, Nevada 14
- Adam Bittner: Nevada 24, New Mexico 13
What our experts think: "Defense has carried New Mexico this season, and that won't change against Nevada. The Lobos offense struggles again, but runs the ball well enough to keep its elite defense off the field long enough." — Austin Curtright, USA TODAY
This article originally appeared on USA TODAY: College football picks: Week 10 expert predictions for Miami-Notre Dame, BYU-Utah, more
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